Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | SNCA | P37840 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435876 | 0.90 | ALDH1A1 (0.58) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL13580513 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL14566202 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL29604975 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL14566281 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL15609523 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL12494830 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL9856621 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL5532432 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E | |
| SCHEMBL12494087 | 0.82 | ALDH1A1 (0.56) | ALDH1A1CYP3A4ALOX15TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252977-B2 | Polynucleotides encoding carotenoid and apocartenoid biosynthetic pathway enzymes in coffee | NESTEC S. A. (CH) | 2012-08-28 | — | — | US | disclosed |
| US-20090178156-A1 | Polynucleotides encoding carotenoid and apocartenoid biosynthetic pathway enzymes in coffee | NESTEC S.A. (CH) | 2009-07-09 | — | — | US | disclosed |
| EP-1924695-A2 | POLYNUCLEOTIDES ENCODING CAROTENOID AND APOCAROTENOID BIOSYNTHETIC PATHWAY | Cornell University (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028115-A2 | POLYNUCLEOTIDES ENCODING CAROTENOID AND APOCAROTENOID BIOSYNTHETIC PATHWAY | CORNELL UNIVERSITY (US) | 2007-03-08 | — | — | WO | disclosed |