Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 5/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280064 | 0.92 | HTR2B (0.38) | HTR2BPDE4DAGPAT2IDO1ALDH1A1 | |
| SCHEMBL4291037 | 0.88 | AGPAT2 (0.44) | AGPAT2IDO1 | |
| SCHEMBL4282211 | 0.87 | HTR6 (0.32) | — | |
| SCHEMBL4278355 | 0.85 | AGPAT2 (0.46) | AGPAT2ALDH1A1RXFP1 | |
| SCHEMBL4282151 | 0.85 | AGPAT2 (0.33) | AGPAT2 | |
| SCHEMBL4281460 | 0.81 | TMPRSS4 (0.34) | HTR2BPDE4DIDO1 | |
| SCHEMBL4285023 | 0.80 | SCN2A (0.33) | — | |
| SCHEMBL4285066 | 0.80 | DYRK3 (0.35) | ALDH1A1 | |
| SCHEMBL4282572 | 0.75 | AGPAT2 (0.41) | AGPAT2ALDH1A1RXFP1 | |
| SCHEMBL4287050 | 0.73 | AGPAT2 (0.33) | AGPAT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419984-B2 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | claimed |
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | CELL THERAPEUTICS, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-7419984-B2 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20040204386-A1 | Pyrimidines and uses thereof | CELL THERAPEUTICS, INC. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204386-A1 | Pyrimidines and uses thereof | LPCAT3, LPCAT1, APRT | HTR2B 4202/4885PDE4D 1418/4885AGPAT2 100/4885 |
| US-20090099183-A1 | PYRIMIDINES AND USES THEREOF | LPCAT3, LPCAT1, APRT | HTR2B 3743/4885PDE4D 1132/4885AGPAT2 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.