SCHEMBL4285475

SCHEMBL4285475

Cc1cccc(C(=O)Nc2nc(NC(=O)c3cccc(C)c3)nc(NC(=O)c3cccc(C)c3)n2)c1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.67
KCNK3 O14649 5/20 0.67
KCNK9 Q9NPC2 5/20 0.67
MEN1 O00255 4/20 0.67
GRM5 P41594 1/20 0.67
KCNH2 Q12809 1/20 0.67
NT5E P21589 1/20 0.64
HDAC8 Q9BY41 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
RXFP1 Q9HBX9 1/20 0.62
NPC1 O15118 6/20 0.61
RAB9A P51151 6/20 0.61
POLB P06746 1/20 0.61
TP53 P04637 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
SCD O00767 1/20 0.57
KDM4E B2RXH2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821364 0.95 GRM5 (0.61) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL2623156 0.94 GRM5 (0.60) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL15305706 0.92 GRM5 (0.66) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL15305709 0.90 GRM5 (0.68) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL16200757 0.90 GRM5 (0.60) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL2623150 0.88 GRM5 (0.55) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL822019 0.87 GRM5 (0.53) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL15305704 0.86 KMT2A (0.65) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL821380 0.86 GRM5 (0.68) KMT2AKCNK3KCNK9MEN1GRM5
SCHEMBL15308203 0.86 KCNK3 (0.61) KMT2AKCNK3KCNK9MEN1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9656969-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-06-09 US disclosed
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-06-09 US disclosed
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-11 US disclosed
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-11 US disclosed
US-8871314-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-8871314-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-20130266744-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2013-10-10 US disclosed
US-20130266744-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2013-10-10 US disclosed
US-20090075048-A1 Cellulose-mixed ester film and method for producing same FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159750-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND PYM1, CNKSR1, MYB KMT2A 519/4885KCNK3 1692/4885KCNK9 1214/4885
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND PYM1, CNKSR1, MYB KMT2A 481/4885KCNK3 1702/4885KCNK9 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.