Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702239 | 0.90 | LPAR1 (0.47) | ALDH1A1MAPK1L3MBTL1LPAR1TDP1 | |
| SCHEMBL13702212 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL4301352 | 0.85 | LPAR1 (0.60) | ALDH1A1MAPK1L3MBTL1LPAR1LMNA | |
| SCHEMBL294341 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL8069055 | 0.78 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL13702210 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL13702213 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL24665788 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL7430396 | 0.77 | TSHR (0.62) | ALDH1A1MAPK1L3MBTL1CDC25BSLC6A2 | |
| SCHEMBL4255720 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1LPAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221684-A1 | Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2007073489-A2 | MOLECULES FOR GENE DELIVERY AND GENE THERAPY, AND METHODS OF USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221684-A1 | Molecules for Gene Delivery and Gene Therapy, and Methods of Use Thereof | ANXA6, STING1, ADM2 | ALDH1A1 2863/4885MAPK1 4787/4885L3MBTL1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.