SCHEMBL4285932

SCHEMBL4285932

Cc1nc(C(F)(F)F)c(CBr)c(=O)n1C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4291653 0.81 KDM5B (0.40) KDM5B
SCHEMBL4290492 0.80 KDM5B (0.33) KDM5B
SCHEMBL4292476 0.78 KDM5B (0.38) KDM5B
SCHEMBL4283815 0.77 KDM5B (0.46) KDM5B
SCHEMBL22016203 0.75 KMT2A (0.33) KDM5B
Iodomethane SCHEMBL4286519 0.74 KDM5B (0.44) KDM5B
SCHEMBL24437107 0.71 KDM5B (0.33) KDM5B
SCHEMBL4289345 0.68
SCHEMBL4295735 0.68 KDM5B (0.35) KDM5B
SCHEMBL4284829 0.61 KDM5B (0.42) KDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009158258-A1 HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-30 WO disclosed