SCHEMBL4291653

SCHEMBL4291653

CCc1nc(C(F)(F)F)c(CBr)c(=O)n1C

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285932 0.81 KDM5B (0.35) KDM5B
SCHEMBL4292476 0.79 KDM5B (0.38) KDM5B
SCHEMBL4284829 0.79 KDM5B (0.42) KDM5B
SCHEMBL4290492 0.77 KDM5B (0.33) KDM5B
SCHEMBL4282519 0.70 KDM5B (0.30) KDM5B
SCHEMBL4291011 0.69
SCHEMBL4295735 0.69 KDM5B (0.35) KDM5B
SCHEMBL26173957 0.60 ALDH1A1 (0.33)
SCHEMBL18850832 0.60 KDM4E (0.36)
SCHEMBL938913 0.59 MPO (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009158258-A1 HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-30 WO disclosed