Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSH | P09668 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692195 | 0.98 | KMT2A (0.67) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL4293438 | 0.96 | KMT2A (0.65) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL4304569 | 0.96 | KMT2A (0.65) | KMT2AOPRK1MAPTCTSBCTSH | |
| Acetic Acid SCHEMBL29222763 | 0.90 | KMT2A (0.57) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL4174305 | 0.83 | KMT2A (0.56) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL3275602 | 0.82 | KMT2A (0.77) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL7171554 | 0.80 | KMT2A (0.74) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL8090833 | 0.79 | KMT2A (1.00) | KMT2AOPRK1MAPTCTSBCTSH | |
| SCHEMBL25097371 | 0.79 | MAPT (0.55) | KMT2AOPRK1MAPTKDM4EHTT | |
| SCHEMBL3984759 | 0.79 | MAPT (0.53) | KMT2AOPRK1MAPTCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | KMT2A 2959/4885OPRK1 1435/4885MAPT 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.