Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 14/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13573934 | 1.00 | CYP26A1 (0.62) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13573939 | 1.00 | CYP26A1 (0.62) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4279149 | 0.88 | CYP3A4 (0.56) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4276636 | 0.77 | CYP26A1 (1.00) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16344079 | 0.76 | ALDH1A1 (0.68) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9683887 | 0.76 | KMT2A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11073226 | 0.76 | KMT2A (0.60) | CYP3A4CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4284732 | 0.76 | CYP26A1 (0.64) | CYP26A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL454293 | 0.73 | RECQL (0.58) | CYP26A1CYP1A2CYP2C19ALDH1A1RECQL | |
| SCHEMBL454294 | 0.73 | RECQL (0.58) | CYP26A1CYP1A2CYP2C19ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153566-A1 | CYP26 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |