SCHEMBL4286330

SCHEMBL4286330

Cn1ncc(OCC(F)(F)F)c(CSC2=NOC(C)(C)C2)c1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.31
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284684 0.84
SCHEMBL4292315 0.82 BRD4 (0.33) CNR2IRAK4
SCHEMBL4292123 0.72 MAPT (0.36) CNR2
SCHEMBL4433372 0.71
SCHEMBL4286381 0.71
SCHEMBL4296086 0.70 BRD4 (0.38) CNR2
SCHEMBL4289345 0.70
SCHEMBL4286011 0.69
SCHEMBL3381416 0.69
SCHEMBL4290676 0.69 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009158258-A1 HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-12-30 WO disclosed