Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110837 | 0.88 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL963777 | 0.75 | MEN1 (0.52) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL7107174 | 0.75 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1PTPN1PTPN6SMN1; SMN2 | |
| SCHEMBL8980650 | 0.75 | MAOB (0.54) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL12513035 | 0.75 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL8489879 | 0.74 | MAPT (0.57) | L3MBTL1MEN1KMT2AMAOBMAPT | |
| SCHEMBL3148815 | 0.73 | MAPT (0.47) | L3MBTL1ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL3292376 | 0.72 | CYP19A1 (0.48) | L3MBTL1ALDH1A1PTPN1CYP19A1PTPN2 | |
| SCHEMBL21775799 | 0.71 | PTGER1 (0.49) | ALDH1A1MEN1KMT2AMAOBALOX5 | |
| SCHEMBL29502992 | 0.71 | SCN9A (0.58) | L3MBTL1MEN1KMT2AMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035004-A1 | PHENYL SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY | Parion Sciences, Inc. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146869-A1 | PHENYL SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY | PARION SCIENCES, INC. (US) | 2007-12-21 | — | — | WO | disclosed |