Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 9/20 | 0.49 |
| ▸ | CES1 | P23141 | 4/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4286916 | 0.80 | CES1 (0.69) | DAGLACES1NCEH1FAAH | |
| SCHEMBL2162450 | 0.79 | DAGLA (0.72) | DAGLACES1NCEH1 | |
| SCHEMBL25456057 | 0.74 | MAPT (0.66) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL11137519 | 0.73 | MAPT (0.77) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL1508071 | 0.73 | MAPT (0.77) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL28609434 | 0.73 | MAPT (0.77) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL4886613 | 0.72 | MAPT (0.73) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL6660129 | 0.71 | MAPT (0.54) | DAGLACES1NCEH1FAAHMAPT | |
| SCHEMBL8102562 | 0.71 | MAPT (0.67) | CES1FAAHMAPTRXFP1ALOX5 | |
| SCHEMBL12813508 | 0.71 | MAPT (0.67) | CES1FAAHMAPTRXFP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |