Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 12/20 | 0.69 |
| ▸ | FAAH | O00519 | 10/20 | 0.53 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.53 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.53 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279402 | 0.84 | CES1 (0.64) | CES1FAAHNCEH1DAGLA | |
| SCHEMBL2163000 | 0.81 | CES1 (1.00) | CES1FAAHNCEH1DAGLAFAAH2 | |
| SCHEMBL12622461 | 0.81 | CES1 (0.60) | CES1FAAHNCEH1DAGLAFAAH2 | |
| SCHEMBL4286697 | 0.80 | DAGLA (0.49) | CES1FAAHNCEH1DAGLA | |
| SCHEMBL10576649 | 0.73 | HPGD (0.54) | CES1FAAHNCEH1 | |
| SCHEMBL2162361 | 0.73 | CES1 (0.60) | CES1FAAH | |
| SCHEMBL5315043 | 0.70 | FAAH (0.51) | CES1FAAH | |
| SCHEMBL12655138 | 0.69 | CES1 (0.46) | CES1FAAH | |
| SCHEMBL25456057 | 0.69 | MAPT (0.66) | CES1FAAH | |
| SCHEMBL10574346 | 0.69 | SMN1; SMN2 (0.55) | FAAHDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |