Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.87 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.80 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.76 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.76 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.76 |
| ▸ | PLG | P00747 | 1/20 | 0.71 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635393 | 0.93 | PLG (0.82) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pachypodol SCHEMBL29929114 | 0.93 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pachypodol SCHEMBL39280 | 0.93 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| SCHEMBL17620251 | 0.89 | ABCG2 (0.77) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pentamethylquercetin SCHEMBL30168918 | 0.89 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pentamethylquercetin SCHEMBL29725289 | 0.89 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pentamethylquercetin SCHEMBL2286327 | 0.89 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| Pentamethylquercetin SCHEMBL30168919 | 0.89 | ABCG2 (1.00) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| SCHEMBL15635199 | 0.88 | ADORA3 (0.83) | ABCG2ABCB1ABCC1KDM4ECYP3A4 | |
| SCHEMBL31259494 | 0.86 | ADORA3 (0.83) | ABCG2ABCB1ABCC1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12514278-B2 | Tobacco-derived composition | R.J. REYNOLDS TOBACCO COMPANY (US) | 2026-01-06 | — | — | US | claimed |
| US-20220346435-A1 | TOBACCO-DERIVED COMPOSITION | REYNOLDS TOBACCO CO R (US) | 2022-11-03 | — | — | US | claimed |
| CN-110432537-B | Tobacco-derived O-methylated flavonoid compositions | R.J.雷诺兹烟草公司 | 2022-08-19 | — | — | CN | claimed |
| US-11412775-B2 | Tobacco-derived composition | R.J. REYNOLDS TOBACCO COMPANY (US) | 2022-08-16 | — | — | US | claimed |
| EP-2906055-B1 | METHOD OF EXTRACTING TOBACCO-DERIVED O-METHYLATED FLAVONOID AND USE THEREOF | REYNOLDS TOBACCO CO R (US) | 2020-12-16 | — | — | EP | claimed |
| CN-110432537-A | The flavonoid composition of the methylation of O- derived from tobacco | REYNOLDS TOBACCO CO R | 2019-11-12 | — | — | CN | claimed |
| EP-2906055-A1 | TOBACCO-DERIVED O-METHYLATED FLAVONOID COMPOSITION | R. J. Reynolds Tobacco Company (US) | 2015-08-19 | — | — | EP | claimed |
| CN-104780791-A | Tobacco-derived O-methylated flavonoid compositions | REYNOLDS TOBACCO CO R | 2015-07-15 | — | — | CN | claimed |
| US-20140096780-A1 | TOBACCO-DERIVED COMPOSITION | R.J. REYNOLDS TOBACCO COMPANY (US) | 2014-04-10 | — | — | US | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | claimed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | claimed |
| US-12514278-B2 | Tobacco-derived composition | R.J. REYNOLDS TOBACCO COMPANY (US) | 2026-01-06 | — | — | US | disclosed |
| US-20220346435-A1 | TOBACCO-DERIVED COMPOSITION | REYNOLDS TOBACCO CO R (US) | 2022-11-03 | — | — | US | disclosed |
| CN-110432537-B | Tobacco-derived O-methylated flavonoid compositions | R.J.雷诺兹烟草公司 | 2022-08-19 | — | — | CN | disclosed |
| US-11412775-B2 | Tobacco-derived composition | R.J. REYNOLDS TOBACCO COMPANY (US) | 2022-08-16 | — | — | US | disclosed |
| WO-2000019998-A1 | COMPOSITIONS AND METHODS OF INHIBITING NEOPLASTIC DISEASES WITH COMPOUNDS RELATED TO LIMOCITRIN AND 5-DESMETHYL SINENSETIN | KGK SYNERGIZE (CA) | 2000-04-13 | — | — | WO | disclosed |
| EP-0019081-B1 | FLAVONE DERIVATIVES, THEIR PREPARATION, THESE NOVEL AND KNOWN FLAVONES AS ANTIVIRAL AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |
| US-4352792-A | 3-Alkoxyflavone antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0019081-A1 | Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-11-26 | — | — | EP | disclosed |