SCHEMBL4287643

SCHEMBL4287643

O=P(O)(O)Cc1ccccc1F

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.55
TAAR1 Q96RJ0 1/20 0.45
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
LMNA P02545 1/20 0.42
PGK1 P00558 4/20 0.42
PGK2 P07205 4/20 0.42
IDO1 P14902 2/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707862 0.84 ACP3 (0.65) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8053801 0.84 ACP3 (0.65) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL778463 0.83 TAAR1 (0.42) ACP3TAAR1LMNAIDO1ALDH1A1
SCHEMBL6429206 0.83 ACP3 (0.52) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9174132 0.80 ACP3 (0.57) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5021454 0.77 KCNH2 (0.42) LMNAIDO1ALDH1A1HPGD
SCHEMBL915357 0.76 ACP3 (0.57) ACP3TAAR1GRIN2DGRIN3BGRIN1
SCHEMBL11499183 0.76 ACP3 (0.57) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28213109 0.76 ACP3 (0.62) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL578080 0.76 SMN1; SMN2 (0.57) ACP3PGK1PGK2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10985446-B1 Physically reconfigurable structurally embedded vascular antenna and method of making UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2021-04-20 US claimed
US-10944178-B1 Physically reconfigurable structurally embedded vascular antenna GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2021-03-09 US claimed
US-10129975-B1 Liquid metal interfaces for flexible and reconfigurable electronics THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-11-13 US claimed
US-20250334727-A1 OPTICAL FILTER, OPTICAL DEVICE, AND LIGHT-ABSORBING COMPOSITION NIPPON SHEET GLASS CO LTD (JP) 2025-10-30 US disclosed
US-20250231329-A1 LIGHT-ABSORBING COMPOSITION, LIGHT-ABSORBING FILM, AND OPTICAL FILTER NIPPON SHEET GLASS CO LTD (JP) 2025-07-17 US disclosed
US-12313869-B2 Optical filter, optical device, and light-absorbing composition NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2025-05-27 US disclosed
US-12287501-B2 Light-absorbing composition, light-absorbing film, and optical filter NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2025-04-29 US disclosed
US-12071542-B2 Light-absorbing composition and optical filter NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2024-08-27 US disclosed
US-20240192414-A1 LAMINATE, VISUAL-LINE TRACKING SYSTEM, AND HEAD-MOUNTED DISPLAY FUJIFILM CORPORATION (JP) 2024-06-13 US disclosed
WO-2024020170-A1 ARYL HYDROCARBON RECEPTOR AGONIST PRODRUGS AND METHODS OF USE THEREOF ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) 2024-01-25 WO disclosed
US-20230400615-A1 OPTICAL FILTER, OPTICAL DEVICE, AND LIGHT-ABSORBING COMPOSITION NIPPON SHEET GLASS COMPANY, LIMITED (JP) 2023-12-14 US disclosed
WO-2006076681-A2 NOVEL COMPOSITIONS FOR PREVENTING AND TREATING NEURODEGENERATIVE AND BLOOD COAGULATION DISORDERS SIRTRIS PHARMACEUTICALS, INC. (US) 2006-07-20 WO disclosed
EP-1220842-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-10 EP disclosed
WO-2001025200-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-12 WO disclosed
US-5593980-A ANTIARTHRITIC AGENTS FOR ADMINISTERING THE UPJOHN COMPANY (US) 1997-01-14 US disclosed
US-5500417-A ANTIARTHRITIC THE UPJOHN COMPANY (US) 1996-03-19 US disclosed
EP-0661978-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS PHARMACIA & UPJOHN COMPANY (US) 1995-07-12 EP disclosed
WO-1994007501-A1 ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1994-04-14 WO disclosed
WO-1993023039-A1 SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS MERCK & CO., INC. (US) 1993-11-25 WO disclosed
US-4299615-A PLANT GROWTH REGULATOR VELSICOL CHEMICAL CORPORATION (US) 1981-11-10 US disclosed