SCHEMBL578080

SCHEMBL578080

O=P(O)(O)Cc1c(F)cccc1F

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.57
PGK1 P00558 9/20 0.48
PGK2 P07205 9/20 0.48
ACP3 P15309 2/20 0.43
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GAA P10253 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12606472 0.86 PGK1 (0.48) SMN1; SMN2PGK1PGK2ACP3GAA
SCHEMBL23091688 0.83 ACP3 (0.46) SMN1; SMN2PGK1PGK2ACP3
SCHEMBL6429206 0.77 ACP3 (0.52) SMN1; SMN2PGK1PGK2ACP3CES2
SCHEMBL4287643 0.76 ACP3 (0.55) SMN1; SMN2PGK1PGK2ACP3
SCHEMBL9174132 0.73 ACP3 (0.57) SMN1; SMN2PGK1PGK2ACP3
SCHEMBL11307755 0.73 SMN1; SMN2 (1.00) SMN1; SMN2PGK1PGK2ACP3POLB
SCHEMBL23884937 0.72 MAPK14 (0.38) SMN1; SMN2CES2CES1GAANPC1
SCHEMBL13512948 0.72 PGK1 (0.44) SMN1; SMN2PGK1PGK2ACP3
SCHEMBL3421056 0.71 SMN1; SMN2 (0.56) SMN1; SMN2PGK1PGK2ACP3
SCHEMBL11121515 0.71 PGK1 (0.52) SMN1; SMN2PGK1PGK2ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10129975-B1 Liquid metal interfaces for flexible and reconfigurable electronics THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2018-11-13 US disclosed
CN-102459290-B Electronic devices comprising novel phosphonic acid surface modifiers 乔治亚州技术研究公司 2017-03-22 CN disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
CN-104641471-A Coating material for oxide thin film transistor POLYERA CORP 2015-05-20 CN disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed
US-20120114974-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS NATIONAL SCIENCE FOUNDATION 2012-05-10 US disclosed
US-20120114974-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS NATIONAL SCIENCE FOUNDATION 2012-05-10 US disclosed
EP-2417142-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS Georgia Tech Research Corporation (US) 2012-02-15 EP disclosed
CN-102099941-A Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RES INST 2011-06-15 CN disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
EP-2304820-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES Georgia Tech Research Corporation (US) 2011-04-06 EP disclosed
WO-2010115854-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS GEORGIA TECH RESEARCH CORPORATION (US) 2010-10-14 WO disclosed
WO-2010007081-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-21 WO disclosed
WO-2010007081-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices EPCAM, EMD, L1CAM SMN1; SMN2 1249/4885PGK1 3140/4885PGK2 3522/4885
US-20120114974-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS EFNA1, PHOSPHO1, EPHA6 SMN1; SMN2 3316/4885PGK1 546/4885PGK2 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.