SCHEMBL4287723

SCHEMBL4287723

C=CCOP(=O)(O)OC(=O)C=C

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.33
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
BTN3A1 O00481 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
MAPT P10636 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
FNTA P49354 2/20 0.31
FNTB P49356 2/20 0.31
PGGT1B P53609 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
LIG1 P18858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6027771 0.86 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27821410 0.82 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3427297 0.81 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL174096 0.80 BTN3A1 (0.40) TSHRALDH1A1CYP3A4BTN3A1LPAR2
SCHEMBL8495295 0.80 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7596703 0.80 BTN3A1 (0.40) TSHRBTN3A1LPAR2LPAR3FNTA
SCHEMBL1116660 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6125496 0.80 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL93378 0.78 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11677557 0.78 BTN3A1 (0.39) TSHRCYP3A4BTN3A1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000755-A1 Oral Care Compositions Comprising Star-Shaped Polymers COLGATE PALMOLIVE COMPANY 2023-01-05 US claimed
US-8530017-B2 Method for preparing styrene-butadiene copolymer using reactive emulsifier and styrene-butadiene copolymer prepared by the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2013-09-10 US claimed
US-20120164363-A1 Method for Preparing Styrene-Butadiene Copolymer Using Reactive Emulsifier and Styrene-Butadiene Copolymer Prepared By the Same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-06-28 US claimed
JP-54138433-A None JP disclosed
JP-54138432-A None JP disclosed
CN-117954779-B Slurry composition, diaphragm and lithium ion battery 深圳好电科技有限公司 2024-07-05 CN disclosed
CN-117954779-A Slurry composition, diaphragm and lithium ion battery 深圳好电科技有限公司 2024-04-30 CN disclosed
CN-107602764-B Hyperbranched copolymer ceramic reinforcing agent and preparation method and application thereof 广东智洁卫浴有限公司 2020-02-14 CN disclosed
US-8530017-B2 Method for preparing styrene-butadiene copolymer using reactive emulsifier and styrene-butadiene copolymer prepared by the same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2013-09-10 US disclosed
US-20120164363-A1 Method for Preparing Styrene-Butadiene Copolymer Using Reactive Emulsifier and Styrene-Butadiene Copolymer Prepared By the Same KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2012-06-28 US disclosed
US-20090081387-A1 Method of Producing Cyclic Polyolefin Film, Cyclic Polyolefin Film Produced by the Production Method, Method of Preparing Liquid Dispersion of Fine Particles, Liquid Dispersion of Fine Particles and Method of Preparing Dope FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
WO-2007032537-A1 METHOD OF PRODUCING CYCLIC POLYOLEFIN FILM, CYCLIC POLYOLEFIN FILM PRODUCED BY THE PRODUCTION METHOD, METHOD OF PREPARING LIQUID DISPERSION OF FINE PARTICLES, LIQUID DISPERSION OF FINE PARTICLES AND METHOD OF PREPARING DOPE FUJIFILM CORPORATION (JP) 2007-03-22 WO disclosed
US-5928850-A WITH OXAZOLIDIONE-TYPE YELLOW COUPLER KONICA CORPORATION (JP) 1999-07-27 US disclosed
EP-0517536-B1 A resinous composition for powder coating NIPPON PAINT CO LTD (JP) 1996-12-18 EP disclosed
US-5266652-A Acrylic ester polymers NIPPON PAINT CO., LTD. (JP) 1993-11-30 US disclosed
EP-0517536-A2 A resinous composition for powder coating NIPPON PAINT CO., LTD. (JP) 1992-12-09 EP disclosed
EP-0101307-B1 AQUEOUS SELF-CURING POLYMERIC BLENDS THE GLIDDEN COMPANY (formerly known as ATKEMIX EIGHT INC.) (US) 1989-05-24 EP disclosed
EP-0101307-A2 Aqueous self-curing polymeric blends THE GLIDDEN COMPANY (formerly known as ATKEMIX EIGHT INC.) (US) 1984-02-22 EP disclosed
JP-S54138433-A PHOTOGRAPHIC ELEMENTS FOR COLOR DIFFUSION TRANSFER PROCESS FUJI PHOTO FILM CO LTD 1979-10-26 JP disclosed
JP-S54138432-A PHOTOGRAPHIC ELEMENTS FOR COLOR DIFFUSION TRANSFER PROCESS FUJI PHOTO FILM CO LTD 1979-10-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000755-A1 Oral Care Compositions Comprising Star-Shaped Polymers STARD7, TAS2R45, KRTCAP2 TSHR 3645/4885ALDH1A1 3926/4885TP53 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.