SCHEMBL6027771

SCHEMBL6027771

C=CC(=O)OP(=O)(O)OCC=O

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.32
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BTN3A1 O00481 1/20 0.32
FNTA P49354 2/20 0.30
FNTB P49356 2/20 0.30
PGGT1B P53609 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4287723 0.86 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27821410 0.80 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8495295 0.79 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1116660 0.78 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6125496 0.78 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL93378 0.77 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL18341416 0.76 BTN3A1 (0.41) TSHRBTN3A1FNTAFNTBPGGT1B
SCHEMBL28122326 0.76 BTN3A1 (0.41) BTN3A1FNTAFNTBPGGT1B
SCHEMBL22799147 0.76 PEPD (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28433337 0.76 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984445-B1 Multi-layer sheet, a manufacturing method of the multi-layer sheet and a molding method of the multi-layer sheet SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-01-10 US disclosed
EP-1270199-A1 LAMINATED SHEET, METHOD FOR PRODUCING LAMINATED SHEET AND METHOD FOR FORMING LAMINATED SHEET SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-01-02 EP disclosed