SCHEMBL4288159

SCHEMBL4288159

O=C(CCCCCCCCC(=O)Oc1ccc(C(=O)c2ccccc2)cc1)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.68
PPARA Q07869 1/20 0.59
PRSS1 P07477 1/20 0.55
PRSS2 P07478 1/20 0.55
PRSS3 P35030 1/20 0.55
KMT2A Q03164 5/20 0.53
MEN1 O00255 3/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
GAA P10253 1/20 0.51
NPC1 O15118 1/20 0.50
ESR1 P03372 1/20 0.50
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
POLB P06746 1/20 0.49
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22666945 1.00 ELANE (0.68) ELANEPPARAPRSS1PRSS2PRSS3
SCHEMBL4274222 1.00 ELANE (0.68) ELANEPPARAPRSS1PRSS2PRSS3
SCHEMBL4288156 0.95 PPARA (0.68) ELANEPPARAPRSS1PRSS2PRSS3
SCHEMBL4274219 0.95 PPARA (0.68) ELANEPPARAPRSS1PRSS2PRSS3
SCHEMBL6765870 0.92 ELANE (0.68) ELANEPPARAKMT2AMEN1ALDH1A1
SCHEMBL6767042 0.92 ELANE (0.68) ELANEPPARAKMT2AMEN1ALDH1A1
SCHEMBL22666944 0.91 ELANE (0.74) ELANEPPARAKMT2AMEN1ALDH1A1
SCHEMBL5935043 0.91 ELANE (0.66) ELANEPPARAKMT2AMEN1ALDH1A1
SCHEMBL9065921 0.86 ELANE (0.59) ELANEPPARAKMT2AMEN1ALDH1A1
SCHEMBL25297232 0.85 PRSS1 (0.70) PRSS1PRSS2PRSS3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2068329-A1 MANUFACTURE METHOD FOR WIRE CABLE INSULATED BY UV CROSSLINKED POLYOLEFIN AND UV IRRADIATION CROSSLINK EQUIPMENT University of Science and Technology of China (CN) 2009-06-10 EP claimed
EP-2509115-A1 Photovoltaic modules comprising a mainly TPO based adhesive integrated backsheet and a front encapsulant film with excellent adhesion to the glass front sheet RENOLIT Belgium N.V. (BE) 2012-10-10 EP disclosed
EP-2068329-A1 MANUFACTURE METHOD FOR WIRE CABLE INSULATED BY UV CROSSLINKED POLYOLEFIN AND UV IRRADIATION CROSSLINK EQUIPMENT University of Science and Technology of China (CN) 2009-06-10 EP disclosed