SCHEMBL6765870

SCHEMBL6765870

CCCCCCCCCCCCCCCCCC(=O)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.68
ESR1 P03372 3/20 0.60
KMT2A Q03164 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PTGS2 P35354 1/20 0.54
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
PPARA Q07869 1/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
ALDH1A1 P00352 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6767042 1.00 ELANE (0.68) ELANEESR1KMT2ASMN1; SMN2PTGS2
SCHEMBL5935043 0.99 ELANE (0.66) ELANEESR1KMT2ASMN1; SMN2PTGS2
SCHEMBL9065921 0.93 ELANE (0.59) ELANEESR1KMT2ASMN1; SMN2PTGS2
SCHEMBL4274222 0.92 ELANE (0.68) ELANEESR1KMT2APPARANPC1
SCHEMBL22666945 0.92 ELANE (0.68) ELANEESR1KMT2APPARANPC1
SCHEMBL4288159 0.92 ELANE (0.68) ELANEESR1KMT2APPARANPC1
SCHEMBL29144800 0.88 HSD17B3 (0.58) ELANEESR1KMT2ASMN1; SMN2NPC1
SCHEMBL4274219 0.88 PPARA (0.68) ELANEESR1KMT2APPARANPC1
SCHEMBL4288156 0.88 PPARA (0.68) ELANEESR1KMT2APPARANPC1
SCHEMBL28868840 0.88 ELANE (0.76) ELANEESR1KMT2APPARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2992044-B1 POLYOLEFIN PIPE UPONOR INNOVATION AB (SE) 2022-01-12 EP disclosed
US-10392496-B2 Polyolefin pipe UPONOR INNOVATION AB (SE) 2019-08-27 US disclosed
US-20180258255-A1 Polyolefin Pipe UPONOR INNOVATION AB (SE) 2018-09-13 US disclosed
US-9963573-B2 Polyolefin pipe UPONOR INNOVATION AB (SE) 2018-05-08 US disclosed
US-20160130420-A1 Polyolefin Pipe UPONOR INNOVATION AB (SE) 2016-05-12 US disclosed
EP-2992044-A1 POLYOLEFIN PIPE Uponor Innovation AB (SE) 2016-03-09 EP disclosed
WO-2014177435-A1 POLYOLEFIN PIPE UPONOR INNOVATION AB (SE) 2014-11-06 WO disclosed
US-20040033380-A1 Process for the manufacture of thermoplastic shrink films SYFAN SAAD (99) LTD. (IL) 2004-02-19 US disclosed
EP-1355976-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS Syfan Saad (99) Ltd. (IL) 2003-10-29 EP disclosed
WO-2002051913-A1 IMPROVED PROCESS FOR THE MANUFACTURE OF THERMOPLASTIC SHRINK FILMS SYFAN SAAD (99) LTD. (IL) 2002-07-04 WO disclosed