Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.72 |
| ▸ | CNR1 | P21554 | 5/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585484 | 0.92 | CNR2 (0.84) | CNR2CNR1KCNH2 | |
| SCHEMBL585474 | 0.86 | CNR2 (0.73) | CNR2CNR1KCNH2 | |
| SCHEMBL584109 | 0.83 | CNR2 (1.00) | CNR2CNR1KCNH2 | |
| SCHEMBL583386 | 0.83 | CNR2 (1.00) | CNR2CNR1KCNH2 | |
| SCHEMBL589193 | 0.82 | CNR2 (0.82) | CNR2CNR1KCNH2 | |
| SCHEMBL585174 | 0.80 | CNR2 (0.66) | CNR2CNR1KCNH2 | |
| SCHEMBL584424 | 0.80 | CNR2 (0.88) | CNR2CNR1KCNH2 | |
| SCHEMBL3927831 | 0.79 | CNR2 (0.79) | CNR2CNR1KCNH2 | |
| SCHEMBL583992 | 0.78 | CNR2 (0.76) | CNR2CNR1KCNH2 | |
| SCHEMBL585586 | 0.76 | CNR2 (0.88) | CNR2CNR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797077-A4 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF I | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1797077-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF I | AstraZeneca AB (SE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006033631-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF I | ASTRAZENECA AB (SE) | 2006-03-30 | — | — | WO | disclosed |