SCHEMBL583386

SCHEMBL583386

CCS(=O)(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2CC1CCC(F)(F)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 1.00
CNR1 P21554 4/20 1.00
KCNH2 Q12809 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL584424 0.94 CNR2 (0.88) CNR2CNR1KCNH2
SCHEMBL585586 0.93 CNR2 (0.88) CNR2CNR1KCNH2
SCHEMBL584109 0.91 CNR2 (1.00) CNR2CNR1KCNH2
SCHEMBL585484 0.90 CNR2 (0.84) CNR2CNR1KCNH2
SCHEMBL589193 0.90 CNR2 (0.82) CNR2CNR1KCNH2
SCHEMBL584127 0.88 CNR2 (0.79) CNR2CNR1KCNH2
SCHEMBL3927831 0.88 CNR2 (0.79) CNR2CNR1KCNH2
SCHEMBL583992 0.86 CNR2 (0.76) CNR2CNR1KCNH2
SCHEMBL585474 0.84 CNR2 (0.73) CNR2CNR1KCNH2
SCHEMBL3920260 0.83 CNR2 (0.73) CNR2CNR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US claimed
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES MINDSTATE DESIGN LABS INC (US) 2025-06-05 US claimed
CN-119497589-A Therapeutic combinations, compositions and methods for designing and producing conditions that promote mental well-being 心境设计实验室股份有限公司 2025-02-21 CN claimed
WO-2023237875-A1 PLURALITY OF GRANULES Artelo Biosciences Limited (GB) 2023-12-14 WO claimed
EP-4259111-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CANNABINOID AGONIST Artello Biosciences Limited (GB) 2023-10-18 EP claimed
CN-116528842-A Pharmaceutical composition comprising a cannabinoid agonist 阿尔特洛生物科学有限公司 2023-08-01 CN claimed
WO-2022123233-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CANNABINOID AGONIST Artelo Biosciences Limited (GB) 2022-06-16 WO claimed
US-20100022610-A1 New Crystalline Forms BOHLIN MARTIN 2010-01-28 US claimed
US-7566788-B2 Crystalline forms ASTRAZENECA AB (SE) 2009-07-28 US claimed
EP-2001856-A1 CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL]-LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS AstraZeneca AB (SE) 2008-12-17 EP claimed
WO-2007108754-A1 CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL] -LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS ASTRAZENECA AB (SE) 2007-09-27 WO claimed
US-20070225346-A1 Crystalline Forms ASTRAZENECA AB (SE) 2007-09-27 US claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 US disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES MINDSTATE DESIGN LABS INC (US) 2025-06-05 US disclosed
WO-2025052179-A1 CANNABINOID FOR USE IN TREATING EYE DISORDERS Artelo Biosciences Limited (GB) 2025-03-13 WO disclosed
WO-2007108754-A1 CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL] -LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS ASTRAZENECA AB (SE) 2007-09-27 WO disclosed
WO-2007108754-A1 CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL] -LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS ASTRAZENECA AB (SE) 2007-09-27 WO disclosed
WO-2007108754-A1 CRYSTALLINE FORMS OF N- {2-TERT -BUTYL -1- [ (4,4- DIF LUOROCYCLOHEXYL) METHYL] -LH-BENZIMIDAZOL-5- YL}ETHANESULFONAMIDE SALTS ASTRAZENECA AB (SE) 2007-09-27 WO disclosed
US-20060264490-A1 Compounds, Compositions Containing Them, Preparation Thereof and Uses Thereof I ASTRAZENECA AB (SE) 2006-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264490-A1 Compounds, Compositions Containing Them, Preparation Thereof and Uses Thereof I F12, C1S, C1R CNR2 83/4885CNR1 54/4885KCNH2 397/4885
US-20250177354-A1 THERAPEUTIC COMBINATIONS, COMPOSITIONS, AND METHODS FOR DESIGNING AND PRODUCING ENTACTOGENIC MINDSTATES CNR2, CNR1, HTR6 CNR2 1/4885CNR1 2/4885KCNH2 4284/4885
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component CNR2, CNR1, LIPC CNR2 1/4885CNR1 2/4885KCNH2 396/4885
US-20100022610-A1 New Crystalline Forms ME1, TST, FH CNR2 4419/4885CNR1 4422/4885KCNH2 2472/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH CNR2 1/4885CNR1 2/4885KCNH2 2779/4885
US-20070225346-A1 Crystalline Forms TST, ME1, FH CNR2 4386/4885CNR1 4362/4885KCNH2 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.