SCHEMBL4289671

SCHEMBL4289671

CCOC(=O)CC1OC(c2cccc(OCCCN(C)CCCc3ccccc3Cl)c2OC)c2cc(Cl)ccc2N(CC(C)(C)C)C1=O

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 18/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4289677 0.99 FDFT1 (0.53) FDFT1
Hydrochloric Acid SCHEMBL4289666 0.99 FDFT1 (0.53) FDFT1
Hydrochloric Acid SCHEMBL4289668 0.99 FDFT1 (0.53) FDFT1
SCHEMBL4292608 0.93 FDFT1 (0.51) FDFT1
SCHEMBL4292617 0.93 FDFT1 (0.51) FDFT1
SCHEMBL4292611 0.93 FDFT1 (0.51) FDFT1
SCHEMBL4291493 0.93 FDFT1 (0.56) FDFT1
Hydrochloric Acid SCHEMBL4291491 0.92 FDFT1 (0.56) FDFT1
Hydrochloric Acid SCHEMBL4291488 0.92 FDFT1 (0.56) FDFT1
Hydrochloric Acid SCHEMBL4291496 0.92 FDFT1 (0.56) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090239839-A1 RECEPTOR ANTAGONIST TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-09-24 US disclosed
US-20070129348-A1 Receptor antagonist TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-06-07 US disclosed
EP-1623710-A1 RECEPTOR ANTAGONIST Takeda Pharmaceutical Company Limited (JP) 2006-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239839-A1 RECEPTOR ANTAGONIST FSHR, NR0B2, NR4A3 FDFT1 3077/4885
US-20070129348-A1 Receptor antagonist FSHR, NR0B2, NR4A3 FDFT1 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.