Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | ALPG | P10696 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032696 | 0.83 | TLR9 (0.55) | KMT2AMEN1MAPK1TDP1ALDH1A1 | |
| SCHEMBL458382 | 0.79 | MGLL (0.52) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL4289960 | 0.79 | MGLL (0.52) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL27650867 | 0.75 | MGLL (0.50) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL5982208 | 0.72 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11036682 | 0.72 | KMT2A (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL5982202 | 0.72 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL157008 | 0.71 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL157009 | 0.71 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL28331876 | 0.71 | KMT2A (0.56) | NPC1RAB9AKMT2AMEN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273705-B2 | Conversion of apoptotic proteins | THE BURNHAM INSTITUTE (US) | 2012-09-25 | — | — | US | disclosed |
| US-20090215984-A1 | CONVERSION OF APOPTOTIC PROTEINS | THE BURNHAM INSTITUTE (US) | 2009-08-27 | — | — | US | disclosed |
| US-7491700-B2 | Conversion of apoptotic proteins | THE BURNHAM INSTITUTE (US) | 2009-02-17 | — | — | US | disclosed |
| US-20070117753-A1 | CONVERSION OF APOPTOTIC PROTEINS | THE BURNHAM INSTITUTE (US) | 2007-05-24 | — | — | US | disclosed |
| US-7176277-B2 | Conversion of apoptotic proteins | THE BURNHAM INSTITUTE (US) | 2007-02-13 | — | — | US | disclosed |
| US-20060193864-A1 | Conversion of apoptotic proteins | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-08-31 | — | — | US | disclosed |
| US-6994979-B2 | Conversion of apoptotic proteins | THE BURNHAM INSTITUTE (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040220097-A1 | Conversion of apoptotic proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-04 | — | — | US | disclosed |
| WO-2004052920-A9 | CONVERSION OF APOPTOTIC PROTEINS | BURNHAM INST (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004052920-A2 | CONVERSION OF APOPTOTIC PROTEINS | THE BURNHAM INSTITUTE (US) | 2004-06-24 | — | — | WO | disclosed |