⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559781 | 1.00 | DPP4 (0.58) | — | |
| SCHEMBL5565016 | 1.00 | DPP4 (0.58) | — | |
| SCHEMBL830 | 1.00 | — | — | |
| SCHEMBL4916236 | 1.00 | DPP4 (0.58) | — | |
| SCHEMBL42393 | 1.00 | — | — | |
| SCHEMBL24932018 | 1.00 | DPP4 (0.58) | — | |
| SCHEMBL29380238 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL3867318 | 0.97 | DPP4 (0.55) | — | |
| Hydrochloric Acid SCHEMBL241514 | 0.97 | ALDH1A1 (0.58) | — | |
| Hydrochloric Acid SCHEMBL4602345 | 0.97 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11003 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084733-B | Preparation method of key intermediate for synthesizing tubulin inhibitor | 重庆皓元生物制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122010861-A | Buronate clamp Process for the preparation of a medicament | 杭州科巢生物科技有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260035372-A1 | METHOD FOR PREPARING (R)-KETOROLAC AND USE THEREOF | Yinuoke Medicine Science and Technology Co LTD (CN) | 2026-02-05 | — | — | US | claimed |
| US-12509434-B2 | Optically resolved Trolox intermediate and method for producing same | PTC THERAPEUTICS, INC. (US) | 2025-12-30 | — | — | US | claimed |
| EP-4284778-B1 | METHOD FOR PREPARING LEVETIRACETAM AND INTERMEDIATES THEREOF | SUZHOU BRIGHTHOPE PHARMATECH CO LTD (CN) | 2025-12-17 | — | — | EP | claimed |
| US-12391710-B2 | Method for the industrial preparation of the disodium salt of ((2S)-3-([1,1′-biphenyl]-4-yl-2-((hydroxy((1R)-1-(((1-(isobutyryloxy)ethoxy)carbonyl)amino)ethyl)phosphoryl) methyl)propanoyl)-l-alanine | KOS THERAPEUTICS, INC. (US) | 2025-08-19 | — | — | US | claimed |
| CN-115960036-B | Preparation method of (R) -3-aminopiperidine dihydrochloride | 大连双硼医药化工有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | claimed |
| CN-119822346-A | Lithium iron phosphate positive electrode material, and preparation method and application thereof | 湖北睿派新能源科技有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-117069591-B | Chiral perovskite crystal piece and preparation method and application thereof | 重庆邮电大学 | 2025-04-01 | — | — | CN | claimed |
| EP-0068038-A1 | (+)-(4R,6S)-(E)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | claimed |
| US-4335057-A | 4-(2',2,2'-Trihalogenoethyl)-cyclobutane-1-sulfonic acid salts with optically active bases | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | claimed |
| EP-0012722-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 3-SUBSTITUTED 2-(2',2'-DIHALOVINYL)-CYCLOPROPANE-1-CARBOXYLIC ACIDS AND THEIR DERIVATIVES; 4-(2',2',2'-TRIHALOETHYL)-CYCLOBUTANE-1-SULPHONIC ACID SALTS AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1981-12-09 | — | — | EP | claimed |
| US-4299967-A | Process for producing optically active 2-(2,2-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3-position, and derivatives thereof, as well as novel 4-(2,2,2-trihalogenoethyl)-cyclobutane-1-sulfonic acid salts | CIBA-GEIGY CORPORATION (US) | 1981-11-10 | — | — | US | claimed |
| EP-0037672-A2 | Process for the preparation of chiral hydantoins, and a novel hydantoin produced by said process and a pharmaceutical composition containing it | PFIZER INC. (US) | 1981-10-14 | — | — | EP | claimed |
| US-4286098-A | HYPOGLYCEMIC AGENTS, TREATMENT OF DIABETES COMPLICATIONS | PFIZER INC. (US) | 1981-08-25 | — | — | US | claimed |
| US-4252744-A | HEATING WITH SODIUM AMIDE OR SODIUM HYDRIDE | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | claimed |
| EP-0023078-A1 | Substituted dibenzo(b,f)thiepin-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1981-01-28 | — | — | EP | claimed |
| US-4190592-A | ION EXCHANGING | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | claimed |
| US-4066567-A | LIQUID CRYSTAL CUMULATIVE DOSIMETER | TEMPLE UNIVERSITY (US) | 1978-01-03 | — | — | US | claimed |