Fluoride

Fluoride

SCHEMBL4290491

F.O=C(O)C(F)(F)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
THRB P10828 1/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
ACLY P53396 2/20 0.33
CA2 P00918 2/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4948143 0.96
SCHEMBL28445979 0.92 ALDH1A1 (0.40) ALDH1A1L3MBTL1THRBTSHRTP53
SCHEMBL29963834 0.92 ALDH1A1 (0.47) ALDH1A1L3MBTL1THRBTSHRTP53
SCHEMBL28573035 0.92 ALDH1A1 (0.40) ALDH1A1L3MBTL1THRBTSHRTP53
Oxalic Acid SCHEMBL27704945 0.88 ALDH1A1 (0.38) ALDH1A1L3MBTL1THRBTSHRTP53
Boric Acid SCHEMBL28336684 0.85 ALDH1A1 (0.36) ALDH1A1L3MBTL1THRBTSHRTP53
Boric Acid SCHEMBL30439850 0.85 ALDH1A1 (0.36) ALDH1A1L3MBTL1THRBTSHRTP53
Boric Acid SCHEMBL25328582 0.82 ALDH1A1 (0.35) ALDH1A1L3MBTL1THRBTSHRTP53
SCHEMBL10838382 0.80 ALDH1A1 (0.38) ALDH1A1L3MBTL1THRBTSHRTP53
SCHEMBL30603826 0.79 ALDH1A1 (0.33) ALDH1A1L3MBTL1THRBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453871-B1 LOW EQUIVALENT WEIGHT IONOMER GORE ENTERPRISE HOLDINGS INC (US) 2009-05-13 EP disclosed
US-7041409-B2 Low equivalent weight ionomer GORE ENTERPRISE HOLDINGS, INC. (US) 2006-05-09 US disclosed
US-7022428-B2 Low equivalent weight ionomer GORE ENTERPRISE HOLDINGS, INC. (US) 2006-04-04 US disclosed
US-20050182215-A1 Low equivalent weight ionomer W. L. GORE & ASSOCIATES, INC. 2005-08-18 US disclosed
US-20050165186-A1 Low Equivalent weight ionomer W. L. GORE & ASSOCIATES, INC. 2005-07-28 US disclosed
US-6861489-B2 Low equivalent weight ionomer GORE ENTERPRISE HOLDINGS, INC. (US) 2005-03-01 US disclosed
EP-1453871-A1 A FLUORINATED IONOMERIC CROSSLINKED COPOLYMER Gore Enterprise Holdings, Inc. (US) 2004-09-08 EP disclosed
US-20030153700-A1 Low equivalent weight ionomer W. L. GORE & ASSOCIATES, INC. 2003-08-14 US disclosed
WO-2003050150-A1 A FLUORINATED IONOMERIC CROSSLINKED COPOLYMER GORE ENTERPRISE HOLDINGS, INC. (US) 2003-06-19 WO disclosed