SCHEMBL4290655

SCHEMBL4290655

CC(=O)NC[C@H]1CN(c2ccc(-c3nnnn3CC#N)c(F)c2)C(=O)O1

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.62
CALML3 P27482 4/20 0.54
MAOB P27338 2/20 0.54
PTGS1 P23219 2/20 0.54
SDHA P31040 2/20 0.54
LMNA P02545 1/20 0.54
F10 P00742 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4364246 0.92 MAOA (0.62) MAOACALML3MAOBPTGS1SDHA
SCHEMBL4363993 0.89 MAOA (0.65) MAOACALML3MAOBPTGS1SDHA
SCHEMBL13819468 0.88 MAOA (0.64) MAOACALML3MAOBPTGS1SDHA
SCHEMBL4372781 0.87 MAOA (0.62) MAOACALML3MAOBPTGS1SDHA
SCHEMBL4362826 0.86 MAOA (0.68) MAOACALML3MAOBPTGS1SDHA
SCHEMBL2898162 0.84 MAOA (0.63) MAOACALML3MAOBPTGS1SDHA
SCHEMBL4153669 0.84 MAOA (0.61) MAOACALML3MAOBPTGS1SDHA
SCHEMBL3182880 0.82 MAOA (0.60) MAOACALML3MAOBPTGS1SDHA
SCHEMBL1394991 0.82 MAOA (0.60) MAOACALML3MAOBPTGS1SDHA
SCHEMBL3328441 0.82 MAOA (0.76) MAOACALML3MAOBPTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009077485-A2 1(2)H-TETRAZOL-5-YL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2009-06-25 WO claimed
EP-2072514-A1 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2009-06-24 EP claimed
WO-2009077485-A2 1(2)H-TETRAZOL-5-YL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2009-06-25 WO disclosed
EP-2072514-A1 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2009-06-24 EP disclosed