SCHEMBL4290974

SCHEMBL4290974

c1ccc(OCCCCCCCCC2CCO2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 2/20 0.53
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
EPHX1 P07099 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133426 1.00 KCNA3 (0.53) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL6132017 0.88 TDP1 (0.52) KCNA3HPGDHTTTDP1TAAR1
SCHEMBL26606320 0.86 TDP1 (0.59) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL28047887 0.86 TDP1 (0.59) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL5686791 0.84 TDP1 (0.61) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL31189818 0.80 KCNA3 (0.44) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL3626061 0.79 TDP1 (0.63) KCNA3HDAC3HDAC4HDAC1HDAC7
SCHEMBL17839026 0.78 MEN1 (0.40) KCNA3HPGDHTTTDP1EPHX1
SCHEMBL9805749 0.77 HRH3 (0.50) HDAC1HPGDHTTTDP1
SCHEMBL3250460 0.77 TDP1 (0.71) TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204968-A1 LYSIS, BINDING AND/OR WASH REAGENT FOR ISOLATING AND/OR PURIFYING NUCLEIC ACIDS QIAGEN GMBH (DE) 2022-06-30 US claimed
US-20090156743-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2009-06-18 US claimed
EP-1999203-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2008-12-10 EP claimed
WO-2007096894-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-08-30 WO claimed
US-20090156743-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2009-06-18 US disclosed
EP-1999203-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2008-12-10 EP disclosed
WO-2007096894-A1 METHOD FOR NUCLEATING POLYMERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-08-30 WO disclosed
EP-0640670-B1 Film-forming silicone emulsion composition TOSHIBA SILICONE (JP) 1998-12-23 EP disclosed
EP-0640670-A2 Film-forming silicone emulsion composition TOSHIBA SILICONE CO., LTD. (JP) 1995-03-01 EP disclosed
US-5359961-A Agglomerates body fluids, but disperses in plumbing systems to non-swelling clay particles and biodegradable end products OIL-DRI CORPORATION OF AMERICA (US) 1994-11-01 US disclosed
US-5101771-A Clay particles, water-soluble organic resin, oleaginous liquid OIL-DRI CORPORATION OF AMERICA (US) 1992-04-07 US disclosed