Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047887 | 0.98 | TDP1 (0.59) | TDP1KCNA3MEN1KMT2ATAAR1 | |
| SCHEMBL26606320 | 0.98 | TDP1 (0.59) | TDP1KCNA3MEN1KMT2ATAAR1 | |
| SCHEMBL3626061 | 0.94 | TDP1 (0.63) | TDP1KCNA3MEN1KMT2ATAAR1 | |
| SCHEMBL3619067 | 0.89 | TDP1 (0.66) | TDP1KCNA3MEN1KMT2ATAAR1 | |
| SCHEMBL8541225 | 0.86 | MGLL (0.50) | TDP1MEN1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL2718081 | 0.85 | HRH3 (0.44) | TDP1KCNA3MEN1KMT2AHDAC3 | |
| SCHEMBL2833284 | 0.85 | HRH3 (0.44) | TDP1KCNA3MEN1KMT2AHDAC3 | |
| SCHEMBL4290974 | 0.84 | KCNA3 (0.53) | TDP1KCNA3TAAR1HDAC3HDAC4 | |
| SCHEMBL1133426 | 0.84 | KCNA3 (0.53) | TDP1KCNA3TAAR1HDAC3HDAC4 | |
| SCHEMBL2720688 | 0.84 | HRH3 (0.42) | TDP1MEN1KMT2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188743-B2 | Cytisine-linked isoflavonoid antineoplastic agents for the treatment of cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180344862-A1 | CYTISINE-LINKED ISOFLAVONOID ANTINEOPLASTIC AGENTS FOR THE TREATMENT OF CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-12-06 | — | — | US | disclosed |
| CN-105246940-B | Optical semiconductor sealing solidification compound | 株式会社大赛璐 | 2018-09-04 | — | — | CN | disclosed |
| CN-105246940-A | Curable composition for sealing optical semiconductor | DAICEL CORP | 2016-01-13 | — | — | CN | disclosed |
| EP-1636209-A1 | EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT | Sumitomo Chemical Company, Limited (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004113327-A1 | EPOXY COMPOUND AND CURED EPOXY RESIN PRODUCT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10188743-B2 | Cytisine-linked isoflavonoid antineoplastic agents for the treatment of cancer | HSD17B4, CYP27A1, SLC25A17 | TDP1 2290/4885KCNA3 4873/4885MEN1 3117/4885 |
| US-20180344862-A1 | CYTISINE-LINKED ISOFLAVONOID ANTINEOPLASTIC AGENTS FOR THE TREATMENT OF CANCER | HSD17B4, CYP27A1, SLC25A17 | TDP1 2290/4885KCNA3 4873/4885MEN1 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.