Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GALR2 | O43603 | 2/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996030 | 0.80 | GALR2 (0.55) | HSD17B10MAPK1ACP1TRPV1GALR2 | |
| SCHEMBL4358367 | 0.79 | KDM4E (0.50) | HSD17B10MAPK1ACP1GALR2GALR1 | |
| SCHEMBL4356830 | 0.79 | GALR2 (0.57) | HSD17B10MAPK1ACP1TRPV1GALR2 | |
| SCHEMBL4122024 | 0.77 | LMNA (0.40) | LMNAMAPTTSHRALDH1A1GAA | |
| SCHEMBL3998850 | 0.73 | GALR2 (0.57) | ACP1GALR2GALR1TP53MAPT | |
| SCHEMBL4001751 | 0.70 | GALR2 (0.52) | HSD17B10MAPK1GALR2GALR1TP53 | |
| SCHEMBL4130166 | 0.69 | GALR2 (0.53) | HSD17B10MAPK1ACP1GALR2GALR1 | |
| SCHEMBL9091199 | 0.69 | SERPINE1 (0.47) | ACP1MAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL16710496 | 0.69 | SERPINE1 (0.47) | ACP1MAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL16710480 | 0.69 | SERPINE1 (0.47) | ACP1MAPTKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805142-A4 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS INC (US) | 2009-06-10 | — | — | EP | claimed |
| EP-1805142-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-07-11 | — | — | EP | claimed |
| WO-2006034474-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | claimed |