Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 14/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.52 |
| ▸ | SNCA | P37840 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293094 | 0.93 | HDAC2 (0.53) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4288498 | 0.93 | HDAC2 (0.53) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4292413 | 0.91 | HDAC6 (0.52) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4169333 | 0.86 | HDAC2 (0.55) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4175980 | 0.84 | HDAC2 (0.58) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5353081 | 0.84 | HDAC2 (0.57) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4293325 | 0.83 | HDAC2 (0.56) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4020428 | 0.83 | HDAC2 (0.60) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4016976 | 0.80 | HDAC2 (0.55) | HDAC2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4288115 | 0.79 | HDAC2 (0.53) | HDAC2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250784-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS CORPORATION | 2005-11-10 | — | — | US | claimed |
| US-20090203010-A1 | MSMB-gene based diagnosis, staging and prognosis of prostate cancer | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2009-08-13 | — | — | US | disclosed |
| US-20050250784-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS CORPORATION | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250784-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC11, HDAC10 | HDAC2 5/4885HDAC3 6/4885HDAC4 11/4885 |
| US-20090203010-A1 | MSMB-gene based diagnosis, staging and prognosis of prostate cancer | MAT2B, DNMT3B, SHBG | HDAC2 3643/4885HDAC3 3834/4885HDAC4 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.