SCHEMBL4292264

SCHEMBL4292264

O=C(O)c1ccccc1C1c2ccccc2Oc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 1.00
ATM Q13315 2/20 0.55
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 1/20 0.46
ALOX5 P09917 1/20 0.46
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29901665 1.00 CYP2C9 (1.00) CYP2C9ATMMAOAMAOBHDAC3
Fluorescin SCHEMBL31164673 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL27403 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL31164674 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
SCHEMBL12037609 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL31214151 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL29370997 0.84 CYP2C9 (0.71) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL1507667 0.82 CYP2C9 (0.69) CYP2C9ATMALDH1A1ALOX15ALOX5
Fluorescin SCHEMBL1938032 0.82 CYP2C9 (0.69) CYP2C9ATMALDH1A1ALOX15ALOX5
SCHEMBL5936698 0.82 CYP2C9 (0.69) CYP2C9MAOBALDH1A1ALOX5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111317731-A FTO inhibitor prepared from 9- (2-carboxyphenyl) xanthene compound and treatment effect thereof 中山大学 2020-06-23 CN claimed
US-20230003702-A1 OPTICAL PH SENSOR Abberior GmbH (DE) 2023-01-05 US disclosed
WO-2021052934-A1 OPTICAL PH SENSOR Abberior GmbH (DE) 2021-03-25 WO disclosed
CN-111317731-A FTO inhibitor prepared from 9- (2-carboxyphenyl) xanthene compound and treatment effect thereof 中山大学 2020-06-23 CN disclosed
CN-111317731-A FTO inhibitor prepared from 9- (2-carboxyphenyl) xanthene compound and treatment effect thereof 中山大学 2020-06-23 CN disclosed
CN-111317731-A FTO inhibitor prepared from 9- (2-carboxyphenyl) xanthene compound and treatment effect thereof 中山大学 2020-06-23 CN disclosed
EP-2120228-B1 Dissolvable thermal direct adhesive label and label assembly including the same AVERY DENNISON CORP (US) 2014-07-23 EP disclosed
EP-2120228-A2 Dissolvable thermal direct adhesive label and label assembly including the same Avery Dennison Corporation Organisation (US) 2009-11-18 EP disclosed
EP-0176252-B1 ASSAY METHOD EMPLOYING FLUORESCENT CELL INCORPORATIVE DYE SYNTEX (U.S.A.) INC. (US) 1991-04-24 EP disclosed
US-4934811-A Apparatus and method for detection of fluorescence or light scatter SYNTEX (U.S.A.) INC. (US) 1990-06-19 US disclosed
US-4748129-A Assay method employing fluorescent cell incorporative dye SNYTEX (U.S.A.) INC. (US) 1988-05-31 US disclosed
US-4676656-A Fluid handling apparatus and method SYNTEX (U.S.A.) INC. (US) 1987-06-30 US disclosed
US-4517580-A LEUCO DYES AND HALO-SUBSTITUTED DIPHENYLTHIOUREA COLOR DEVELOPERS;THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1985-05-14 US disclosed