SCHEMBL4292745

SCHEMBL4292745

Nc1cccc2c1C(=O)c1cc(S(=O)(=O)O)c(S(=O)(=O)O)c(N)c1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.54
PGAM1 P18669 1/20 0.49
DAPK1 P53355 1/20 0.48
PTPRC P08575 1/20 0.46
MAOA P21397 2/20 0.44
MAOB P27338 1/20 0.44
GNG2 P59768 4/20 0.43
GNB1 P62873 4/20 0.43
CSNK1A1 P48729 2/20 0.42
CSNK1D P48730 2/20 0.42
CSNK1G1 Q9HCP0 2/20 0.42
FGR P09769 1/20 0.42
PIM1 P11309 1/20 0.42
DYRK1A Q13627 1/20 0.42
HIPK2 Q9H2X6 1/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPK1 P28482 4/20 0.42
MEN1 O00255 3/20 0.42
POLB P06746 3/20 0.42
KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4298629 0.82 ADORA2A (0.56) ADORA2APGAM1DAPK1PTPRCMAOA
SCHEMBL2294438 0.80 ADORA2A (0.61) ADORA2APGAM1DAPK1PTPRCMAOA
SCHEMBL2789317 0.79 DAPK1 (0.56) ADORA2APGAM1DAPK1MAOAMAOB
SCHEMBL12477906 0.79 ADORA2A (0.59) ADORA2APGAM1DAPK1PTPRCMAOA
SCHEMBL14690148 0.79 ADORA2A (0.59) ADORA2APGAM1DAPK1PTPRCMAOA
Sulfuric Acid SCHEMBL8643234 0.78 ADORA2A (0.73) ADORA2ADAPK1PTPRCMAOAMAOB
SCHEMBL3079411 0.77 PGAM1 (0.64) ADORA2APGAM1DAPK1MAOAMAOB
Sulfuric Acid SCHEMBL28138466 0.76 ADORA2A (0.85) ADORA2ADAPK1PTPRCMAOAMAOB
SCHEMBL419737 0.75 PGAM1 (0.66) PGAM1DAPK1MAOAGNG2GNB1
SCHEMBL2295728 0.75 ADORA2A (0.59) ADORA2APGAM1PTPRCMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106608846-A Production method for preparing 2-chloro-5-chloromethylpyridine from cyclopentadiene-acrolein 江苏吉华化工有限公司 2017-05-03 CN claimed
CN-106397308-A Process for preparing 2-chloro-5-chloromethylpyridine from trimethylpyridine-phosphamide 江苏吉华化工有限公司 2017-02-15 CN claimed
CN-106608846-A Production method for preparing 2-chloro-5-chloromethylpyridine from cyclopentadiene-acrolein 江苏吉华化工有限公司 2017-05-03 CN disclosed
CN-106397308-A Process for preparing 2-chloro-5-chloromethylpyridine from trimethylpyridine-phosphamide 江苏吉华化工有限公司 2017-02-15 CN disclosed
US-20090297890-A1 Anode for Bioelectric Power Generation And Power Generation Method And Apparatus Utilizing Same EBARA CORPORATION (JP) 2009-12-03 US disclosed
US-20090142627-A1 Biological Power Generator, and Method of Treating Organic Solid Pollutant-Containing Waste, a Method of Treating Organic Polymeric Substance-Containing Wastewater, a Method of Treating Organic Substance-Containing Wastewater, as Well as Apparatuses for Implementing These Treatment Methods EBARA CORPORATION (JP) 2009-06-04 US disclosed
EP-1947716-A1 ANODE FOR BIOLOGICAL POWER GENERATION AND POWER GENERATION METHOD AND DEVICE UTILIZING IT EBARA CORPORATION (JP) 2008-07-23 EP disclosed
EP-1939968-A1 BIOLOGICAL POWER PLANT, AND METHOD OF TREATING ORGANIC SOLID CONTAMINANT-CONTAINING WASTE, METHOD OF TREATING ORGANIC HIGH MOLECULAR SUBSTANCE-CONTAINING LIQUID WASTE AND METHOD OF TREATING ORGANIC SUBSTANCE-CONTAINING LIQUID WASTE BY USING THE BIOLOGICAL POWER PLANT, AND APPARATUS FOR CONDUCTING THESE METHODS EBARA CORPORATION (JP) 2008-07-02 EP disclosed