Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 3/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | COMT | P21964 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157041 | 0.98 | KDM4E (0.70) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL16407906 | 0.89 | KDM4E (0.66) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL11515706 | 0.88 | KDM4E (0.64) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL11796771 | 0.86 | KDM4E (0.62) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL114710 | 0.85 | KDM4E (0.74) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL15854518 | 0.83 | KDM4E (0.77) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL4564667 | 0.83 | KDM4E (0.96) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL10157043 | 0.83 | MAOA (0.71) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL10156363 | 0.82 | KDM4E (0.70) | KDM4ENPC1HTTL3MBTL1RAB9A | |
| SCHEMBL10839031 | 0.82 | KDM4E (0.70) | KDM4ENPC1HTTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | KDM4E 3068/4885NPC1 367/4885HTT 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.