Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441730 | 1.00 | BDKRB1 (0.40) | BDKRB1ALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3441702 | 0.92 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL3441720 | 0.92 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL4300734 | 0.92 | BDKRB1 (0.40) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL3441652 | 0.91 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL3441734 | 0.91 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3441654 | 0.91 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL3441794 | 0.91 | BDKRB1 (0.40) | BDKRB1ALDH1A1 | |
| SCHEMBL4290344 | 0.91 | BDKRB1 (0.40) | BDKRB1CYP3A4 | |
| SCHEMBL3441844 | 0.90 | BDKRB1 (0.39) | BDKRB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318769-B2 | Substituted sulfonamide compounds | GRUENETHAL GMBH (DE) | 2012-11-27 | — | — | US | claimed |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | claimed |
| US-8318769-B2 | Substituted sulfonamide compounds | GRUENETHAL GMBH (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264400-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, TRPV1 | BDKRB1 1/4885ALDH1A1 1956/4885CYP3A4 1382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.