Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 10/20 | 0.72 |
| ▸ | CES1 | P23141 | 5/20 | 0.53 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162438 | 0.84 | DAGLA (1.00) | DAGLACES1NCEH1FAAH | |
| SCHEMBL2164447 | 0.82 | DAGLA (0.65) | DAGLACES1NCEH1FAAH | |
| SCHEMBL4284832 | 0.76 | CES1 (0.62) | DAGLACES1NCEH1FAAH | |
| SCHEMBL2162463 | 0.75 | DAGLA (0.56) | DAGLACES1NCEH1FAAH | |
| SCHEMBL4285196 | 0.71 | ATM (0.44) | DAGLACES1NCEH1 | |
| SCHEMBL4282566 | 0.70 | DAGLA (0.62) | DAGLACES1NCEH1 | |
| SCHEMBL2162839 | 0.69 | CES1 (1.00) | DAGLACES1NCEH1 | |
| SCHEMBL2162583 | 0.69 | DAGLA (1.00) | DAGLACES1NCEH1FAAH | |
| SCHEMBL1706448 | 0.69 | CES1 (0.39) | DAGLACES1NCEH1 | |
| SCHEMBL11959477 | 0.68 | CES1 (0.53) | DAGLACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |