Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557714 | 0.88 | NPC1 (0.45) | ATMTDP1L3MBTL1CYP2D6 | |
| SCHEMBL4284832 | 0.80 | CES1 (0.62) | DAGLASIGMAR1CES1NCEH1 | |
| SCHEMBL4280672 | 0.80 | DAGLA (0.41) | ATMTDP1L3MBTL1DAGLASIGMAR1 | |
| SCHEMBL4282566 | 0.79 | DAGLA (0.62) | DAGLACES1NCEH1 | |
| SCHEMBL2162419 | 0.76 | FAAH (0.53) | DAGLA | |
| SCHEMBL2162404 | 0.75 | DAGLA (0.73) | DAGLACES1NCEH1 | |
| SCHEMBL4279402 | 0.74 | CES1 (0.64) | DAGLACES1NCEH1 | |
| SCHEMBL12064926 | 0.73 | DAGLA (0.56) | ATMTDP1L3MBTL1DAGLACES1 | |
| SCHEMBL7220481 | 0.72 | L3MBTL1 (0.44) | TDP1L3MBTL1 | |
| SCHEMBL8094527 | 0.71 | SIGMAR1 (0.71) | L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |