Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788804 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7907717 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7789360 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7789291 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL4198536 | 0.98 | HSD17B3 (0.70) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL19757444 | 0.95 | HSD17B3 (0.65) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL1091479 | 0.92 | HSD17B3 (0.69) | HSD17B3HDAC1HDAC8HTR7STS | |
| SCHEMBL13085847 | 0.90 | HSD17B3 (0.85) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL13085794 | 0.90 | HSD17B3 (0.85) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL18753070 | 0.88 | HSD17B3 (0.84) | HSD17B3HTR7THRATHRBSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110846050-B | Bent azo liquid crystal compound and preparation method and application thereof | 武汉轻工大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-110846050-A | Bent azo liquid crystal compound and preparation method and application thereof | 武汉轻工大学 | 2020-02-28 | — | — | CN | disclosed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIO-PROJET (FR) | 2009-10-22 | — | — | US | disclosed |
| EP-1650186-B1 | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-06-04 | — | — | EP | disclosed |
| WO-2006043149-A9 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2006-08-10 | — | — | WO | disclosed |
| WO-2006043149-A2 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET (FR) | 2006-04-27 | — | — | WO | disclosed |
| EP-1650186-A1 | Novel dicarboxylic acid derivatives | BIOPROJET (FR) | 2006-04-26 | — | — | EP | disclosed |
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264469-A1 | NOVEL DICARBOXYLIC ACID DERIVATIVES | S1PR2, S1PR1, S1PR5 | HSD17B3 1937/4885HDAC1 431/4885HDAC8 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.