Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788804 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7907717 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL7789360 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL4293741 | 1.00 | HSD17B3 (0.71) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL4198536 | 0.98 | HSD17B3 (0.70) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL19757444 | 0.95 | HSD17B3 (0.65) | HSD17B3HDAC1HDAC8HTR7THRA | |
| SCHEMBL1091479 | 0.92 | HSD17B3 (0.69) | HSD17B3HDAC1HDAC8HTR7STS | |
| SCHEMBL13085847 | 0.90 | HSD17B3 (0.85) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL13085794 | 0.90 | HSD17B3 (0.85) | HSD17B3HTR7THRATHRBSTS | |
| SCHEMBL18753070 | 0.88 | HSD17B3 (0.84) | HSD17B3HTR7THRATHRBSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110846050-B | Bent azo liquid crystal compound and preparation method and application thereof | 武汉轻工大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-110846050-A | Bent azo liquid crystal compound and preparation method and application thereof | 武汉轻工大学 | 2020-02-28 | — | — | CN | disclosed |
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-6191182-B1 | SUBJECTING P-HALOPHENYL ALKYL KETONE TO AMINOLYSIS WITH CYCLIC SECONDARY AMINE TO FORM CYCLIC AMINE-SUBSTITUTED PHENYL ALKYL KETONE; HALOGINATION AND REACTING WITH AMINE COMPOUND; STEVENS REARRANGEMENT UNDER BASIC CONDITION | CIBA SPECIALTY CHEMCIALS CORPORATION | 2001-02-20 | — | — | US | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |
| US-5977357-A | Phenyl alkyl ketone substituted by cyclic amine and a process for the preparation thereof | CIBA SPECIALTY CHEMICAL CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5795985-A | Phenyl alkyl ketone substituted by cyclic amine and a process for the preparation thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |