Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288633 | 0.92 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL4293921 | 0.89 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3012238 | 0.89 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3000828 | 0.87 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3008063 | 0.84 | CSNK2A2 (0.48) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3007403 | 0.83 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL12312002 | 0.83 | CSNK2A2 (0.42) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL12690915 | 0.82 | ALOX5 (0.48) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3003614 | 0.82 | MAPK1 (0.53) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL3010671 | 0.82 | ABCB1 (0.40) | MEN1KMT2AMAPTCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069321-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | Digital Biotech Co., Ltd. (KR) | 2009-06-17 | — | — | EP | disclosed |
| US-7514158-B2 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-07 | — | — | US | disclosed |
| WO-2008041826-A1 | NOVEL BENZOFURAN TYPE DERIVATIVES, A COMPOSITION COMPRISING THE SAME FOR TREATING OR PREVENTING COGNITIVE DYSFUNCTION AND THE USE THEREOF | DIGITAL BIOTECH CO., LTD (KR) | 2008-04-10 | — | — | WO | disclosed |
| US-20050275341-A1 | Coumarin compound | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050275341-A1 | Coumarin compound | XPO1, VKORC1, XPO5 | CSNK2A2 1175/4885CSNK2B 1497/4885CSNK2A1 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.