Phenol

Phenol

SCHEMBL4294325

CC(O)O.Oc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.69
CA1 P00915 1/20 0.69
CA2 P00918 1/20 0.69
GLA P06280 1/20 0.69
CA3 P07451 1/20 0.69
CA4 P22748 1/20 0.69
CA9 Q16790 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
CA14 Q9ULX7 1/20 0.69
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
ESR1 P03372 8/20 0.46
ESR2 Q92731 7/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ADRA2A P08913 1/20 0.44
ADRA2C P18825 1/20 0.44
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL8375278 0.94 CA12 (0.69) CA12CA1CA2GLACA3
Phenol SCHEMBL7929451 0.91 CA12 (0.65) CA12CA1CA2GLACA3
Phenol SCHEMBL7115665 0.88 CA12 (0.61) CA12CA1CA2GLACA3
Phenol SCHEMBL5875310 0.88 CA12 (0.61) CA12CA1CA2GLACA3
Phenol SCHEMBL2898082 0.88 CA12 (0.61) CA12CA1CA2GLACA3
Phenol SCHEMBL21753960 0.88 CA12 (0.69) CA12CA1CA2GLACA3
Phenol SCHEMBL2551294 0.86 CA12 (0.58) CA12CA1CA2GLACA3
Phenol SCHEMBL11227306 0.85 CA12 (0.65) CA12CA1CA2GLACA3
Phenol SCHEMBL9302707 0.85 CA12 (0.65) CA12CA1CA2GLACA3
Phenol SCHEMBL9396101 0.85 CA12 (0.65) CA12CA1CA2GLACA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275077-A1 Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides OXYRANE (UK) LIMITED (GB) 2009-11-05 US disclosed
US-20070281339-A1 Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides OXYRANE UK LIMITED (GB) 2007-12-06 US disclosed
EP-1756281-A2 METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS CSIR (ZA) 2007-02-28 EP disclosed
WO-2005100569-A2 METHODS FOR THE PREPARATION OF OPTICALLY ACTIVE EPOXIDES AND VICINAL DIOLS FROM STYRENE EPOXIDES USING ENANTIOSELECTIVE EPOXIDE HYDROLASES DERIVED FROM YEASTS CSIR (ZA) 2005-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275077-A1 Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides EPHX2, EPHX1, DERA CA12 2202/4885CA1 2078/4885CA2 2324/4885
US-20070281339-A1 Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides DERA, ERG28, EPHX2 CA12 3180/4885CA1 3174/4885CA2 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.