Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29604675 | 1.00 | TAAR1 (0.62) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL15178307 | 0.95 | TAAR1 (0.61) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL11862122 | 0.93 | TAAR1 (0.59) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL28945271 | 0.93 | TAAR1 (0.59) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL30712274 | 0.93 | TAAR1 (0.59) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL11696002 | 0.93 | TAAR1 (0.59) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL15272035 | 0.93 | TAAR1 (0.59) | TAAR1CALM1HDAC1HDAC3HDAC2 | |
| SCHEMBL18414428 | 0.89 | TRPV1 (0.52) | TAAR1CALM1TRPV1MAPT | |
| SCHEMBL429483 | 0.89 | TAAR1 (0.67) | TAAR1CALM1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL108050 | 0.88 | CALM1 (0.72) | TAAR1CALM1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697752-A1 | THERMOLABILE FRAGRANCE STORAGE SUBSTANCES OF FRAGRANT KETONES | Henkel AG & Co. KGaA (DE) | 2020-08-26 | — | — | EP | claimed |
| WO-2019076588-A1 | THERMOLABILE FRAGRANCE STORAGE SUBSTANCES OF FRAGRANT KETONES | HENKEL AG & CO. KGAA (DE) | 2019-04-25 | — | — | WO | claimed |
| WO-2024234014-A1 | SUBLINGUAL SPRAY FORMULATIONS OF PSYCHEDELICS | SPIRITUS BIOSCIENCE, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20230355583-A1 | METHODS FOR DELIVERY OF PSYCHEDELIC MEDICATIONS BY INHALATION AND SYSTEMS FOR PERFORMING THE METHODS | CYBIN IRL LIMITED (IE) | 2023-11-09 | — | — | US | disclosed |
| US-20230219942-A1 | COMPOUNDS COMPRISING A THREE RING CORE AS PD-1/PD-L1 BLOCKERS | RELIVE THERAPEUTICS INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| WO-2023019369-A1 | COMPOSITIONS COMPRISING NON-RACEMIC MIXTURES OF (R)- AND (S)-3,4-METHYLENEDIOXYMETHAMPHETAMINE OR (R) AND (S) N-METHYL-1,3-BENZODIOXOLYLBUTANAMINE AND USES THEREOF | PHARMALA BIOTECH INC. (CA) | 2023-02-23 | — | — | WO | disclosed |
| EP-4106822-A1 | BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING NEUTRALIZING AGENT | Henkel AG & Co. KGaA (DE) | 2022-12-28 | — | — | EP | disclosed |
| US-20220071933-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2022-03-10 | — | — | US | disclosed |
| WO-2021161083-A1 | AN EFFICIENT PROCESS FOR PREPARATION OF ACYL DERIVATIVES OF ALKYLENEDIOXYBENZENES | ANTHEA AROMATICS PRIVATE LIMITED (IN) | 2021-08-19 | — | — | WO | disclosed |
| EP-3346834-B1 | SUBSTITUTED METHYLENEDIOXYBENZYL COMPOUNDS AND THEIR USE AS SYNERGISTS | ENDURA SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| EP-3713921-A1 | HYDROLYTICALLY LABILE HETEROCYCLES OF ODORIFEROUS KETONES OR ODORIFEROUS ALDEHYDES | Henkel AG & Co. KGaA (DE) | 2020-09-30 | — | — | EP | disclosed |
| US-20040161404-A1 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-19 | — | — | US | disclosed |
| EP-1439157-A2 | Method for producing Suzuki coupling compound catalysed by a nickel compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-5932749-A | Asymmetric synthesis of R-α-propyl-piperonyl amine and its analogs | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0888329-A1 | NOVEL ASYMMETRIC SYNTHESIS OF R-$g(a)-PROPYL-PIPERONYL AMINE AND ITS ANALOGS | Du Pont Pharmaceuticals Company (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034887-A1 | NOVEL ASYMMETRIC SYNTHESIS OF R-α-PROPYL-PIPERONYL AMINE AND ITS ANALOGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| EP-0408585-A4 | IMMOBILIZED ARTIFICIAL MEMBRANES | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0408585-A1 | IMMOBILIZED ARTIFICIAL MEMBRANES | Purdue Research Foundation (US) | 1991-01-23 | — | — | EP | disclosed |
| US-4927879-A | CHROMATOGRAPHY SUPPORTS | PURDUE RESEARCH FOUNDATION (US) | 1990-05-22 | — | — | US | disclosed |
| WO-1989008130-A1 | IMMOBILIZED ARTIFICIAL MEMBRANES | PURDUE RESEARCH FOUNDATION (US) | 1989-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220071933-A1 | COMBINATION REMEDY | GPR119, GLP1R, GIPR | TAAR1 457/4885CALM1 2249/4885HDAC1 3229/4885 |
| US-20230219942-A1 | COMPOUNDS COMPRISING A THREE RING CORE AS PD-1/PD-L1 BLOCKERS | CD274, PDCD1, PDCD1LG2 | TAAR1 2757/4885CALM1 3384/4885HDAC1 862/4885 |
| US-20230355583-A1 | METHODS FOR DELIVERY OF PSYCHEDELIC MEDICATIONS BY INHALATION AND SYSTEMS FOR PERFORMING THE METHODS | PNMT, CNR2, CNR1 | TAAR1 17/4885CALM1 37/4885HDAC1 4297/4885 |
| US-20040161404-A1 | Method for producing coupling compound | PYM1, MALT1, BET1 | TAAR1 532/4885CALM1 2997/4885HDAC1 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.