Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287126 | 0.83 | KDM5B (0.42) | KDM5BCASRMAOAMAOBMEN1 | |
| SCHEMBL4292476 | 0.80 | KDM5B (0.38) | KDM5BKDM4EHPGDMAOAMAOB | |
| SCHEMBL4284829 | 0.77 | KDM5B (0.42) | KDM5BCASR | |
| SCHEMBL4283815 | 0.75 | KDM5B (0.46) | KDM5BCASR | |
| SCHEMBL4282510 | 0.73 | CASR (0.41) | KDM5BCASRALDH1A1 | |
| Iodomethane SCHEMBL4286519 | 0.73 | KDM5B (0.44) | KDM5BCASR | |
| SCHEMBL4290492 | 0.66 | KDM5B (0.33) | KDM5BMAOAMAOB | |
| SCHEMBL33834 | 0.66 | KMT2A (0.70) | MAOAMAOBMEN1KMT2AL3MBTL1 | |
| SCHEMBL27473281 | 0.65 | TNF (0.36) | KDM4EHPGDALDH1A1MAOAMAOB | |
| SCHEMBL13259552 | 0.65 | POLB (0.35) | KDM4EHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158258-A1 | HERBICIDAL DIHYDRO OXO SIX-MEMBERED AZINYL ISOXAZOLINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |