SCHEMBL13259552

SCHEMBL13259552

CCOc1c(C)c(C(F)(F)F)nn1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 5/20 0.35
KMT2A Q03164 5/20 0.35
MAPT P10636 4/20 0.35
MEN1 O00255 4/20 0.35
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HTT P42858 2/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 5/20 0.34
CYP1A2 P05177 5/20 0.34
CYP2C9 P11712 5/20 0.34
CYP2C19 P33261 5/20 0.34
KDM4E B2RXH2 4/20 0.34
HPGD P15428 4/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2D6 P10635 2/20 0.34
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ALOX5AP P20292 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5369514 0.86 LMNA (0.36) POLBL3MBTL1KMT2AMAPTMEN1
SCHEMBL5369988 0.81 LMNA (0.31) L3MBTL1KMT2AMAPTMEN1LMNA
SCHEMBL14466825 0.81 POLB (0.41) POLBL3MBTL1KMT2AMAPTMEN1
SCHEMBL537595 0.78 SMN1; SMN2 (0.38) POLBL3MBTL1KMT2AMAPTMEN1
SCHEMBL5340378 0.77 LMNA (0.51) POLBL3MBTL1KMT2AMAPTMEN1
SCHEMBL5371331 0.75 POLB (0.32) POLBL3MBTL1
SCHEMBL24553662 0.75 MPO (0.34) L3MBTL1MAPTSMN1; SMN2GAAALDH1A1
SCHEMBL21737449 0.73 POLB (0.35) POLBKMT2AMAPTMEN1LMNA
SCHEMBL13242998 0.71 MAPT (0.38) POLBL3MBTL1KMT2AMAPTMEN1
SCHEMBL13243023 0.70 MEN1 (0.40) POLBL3MBTL1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010087294-A1 TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PROCESS FOR PRODUCING THE SAME AND PESTICIDE CONTAINING THE SAME ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-08-05 WO disclosed