⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517724 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL24624048 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL24624045 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL24624068 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL24624356 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL11355044 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL6511678 | 0.67 | — | — | |
| SCHEMBL11309485 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL9359483 | 0.67 | — | — | |
| SCHEMBL24624049 | 0.67 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137718-A1 | Nucleozymes | UNIVERSITY OF MONTREAL AND MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-09-26 | — | — | US | claimed |
| EP-0625192-B1 | NUCLEOZYMES | MASSACHUSETTS INST TECHNOLOGY (US) | 2002-05-22 | — | — | EP | claimed |
| EP-0625192-A1 | NUCLEOZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-11-23 | — | — | EP | claimed |
| WO-1993015187-A1 | NUCLEOZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1993-08-05 | — | — | WO | claimed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| CN-106337046-B | Method for synthesizing bifunctional complexes | 纽韦卢森公司 | 2021-03-23 | — | — | CN | disclosed |
| US-20200216836-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2020-07-09 | — | — | US | disclosed |
| US-9574189-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2017-02-21 | — | — | US | disclosed |
| CN-106337046-A | Method for synthesis of bifunctional complex | 纽韦卢森公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-102838654-B | The method of synthetic difunctional compound | NUEVOLUTION AS (DK) | 2016-05-18 | — | — | CN | disclosed |
| CN-1720331-B | Method for synthesizing bifunctional complexes | NUEVOLUTION AS | 2013-01-02 | — | — | CN | disclosed |
| EP-0643778-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0625192-A1 | NUCLEOZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0544824-A4 | NUCLEASE RESISTANT, PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 1994-09-21 | — | — | EP | disclosed |
| WO-1993020242-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993015187-A1 | NUCLEOZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1993-08-05 | — | — | WO | disclosed |
| EP-0544824-A1 | NUCLEASE RESISTANT, PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION. | ISIS PHARMACEUTICALS INC (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5214135-A | N-protected-2'-O-methyl-ribonucleosides and N-protected 2'-O-methyl-3'-cyanoethyl-N-,N-diisopropyl phosphoramidite ribonucleosides | CHEMGENES CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992002258-A1 | NUCLEASE RESISTANT, PYRIMIDINE MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1992-02-20 | — | — | WO | disclosed |