⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006574 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL1008577 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL1006326 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL7979768 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL425479 | 0.97 | — | — | |
| SCHEMBL7610633 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL430013 | 0.97 | — | — | |
| SCHEMBL1008919 | 0.97 | ALDH1A1 (0.50) | — | |
| SCHEMBL5173665 | 0.91 | ALDH1A1 (0.41) | — | |
| SCHEMBL4392852 | 0.91 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956977-B | Biphenyl compound, pharmaceutical composition, and preparation methods and applications thereof | 朗捷睿(苏州)生物科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2023236924-A1 | BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-12-14 | — | — | WO | claimed |
| CN-114956977-A | Biphenyl compound, pharmaceutical composition, preparation method and application thereof | 朗捷睿(苏州)生物科技有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-11345693-B2 | Compounds, salts thereof and methods for treatment of diseases | ACADIA PHARMACEUTICALS INC. (US) | 2022-05-31 | — | — | US | claimed |
| US-20210078972-A1 | QUINOLINE OR QUINAZOLINE COMPOUND AND APPLICATION THEREOF | JINAN UNIVERSITY (CN) | 2021-03-18 | — | — | US | claimed |
| EP-3778585-A1 | QUINOLINE OR QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Haihe Biopharma Co., Ltd. (CN) | 2021-02-17 | — | — | EP | claimed |
| CN-112351971-A | Quinoline or quinazoline compound and application thereof | 上海海和药物研究开发股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | claimed |
| US-10821103-B2 | Substituted pyridinone-containing trycyclic compounds, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-11-03 | — | — | US | claimed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | claimed |
| US-20040186265-A1 | Polythiophenes and devices thereof | XEROX CORPORATION | 2004-09-23 | — | — | US | claimed |
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | claimed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | claimed |
| EP-0928815-A1 | WATER-SOLUBLE DISAZO COMPOUNDS, WATER-BASE INK COMPOSITION, AND COLORED OBJECT | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-07-14 | — | — | EP | claimed |
| US-5753740-A | OXAZOLINE COMPOUND OR MELAMINE RESIN HARDENER | NIPPON PAINT CO., LTD. (JP) | 1998-05-19 | — | — | US | claimed |
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | claimed |
| EP-0659855-A2 | Water-based coating composition | NIPPON PAINT CO., LTD. (JP) | 1995-06-28 | — | — | EP | claimed |
| EP-0323757-B1 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES (JP) | 1995-05-10 | — | — | EP | claimed |
| US-4940492-A | Colorant mixtures containing isoquinoline derivatives, use thereof in printing inks, and novel isoquinoline derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-10 | — | — | US | claimed |