Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302586 | 0.87 | MAPT (0.48) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL3219619 | 0.82 | MAPT (0.40) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL14519048 | 0.78 | HPGD (0.74) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL14468246 | 0.78 | MAPT (0.74) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL4302590 | 0.78 | MAPT (0.48) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL2831822 | 0.76 | MAPT (0.61) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL4296343 | 0.76 | RECQL (0.58) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL13718982 | 0.76 | MAPT (0.67) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL3200271 | 0.73 | MAPT (0.38) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL8666821 | 0.71 | RECQL (0.54) | MAPTALDH1A1NPSR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | claimed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | claimed |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | disclosed |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | TANABE SATOSHI | 2009-10-29 | — | — | US | disclosed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-06-14 | — | — | US | disclosed |
| WO-2005102050-A1 | FLEA CONTROL AGENT CONTAINING N-SUBSTITUTED INDOLE DERIVATIVE | NIPPON KAYAKU KABUSHIKIKAISHA (JP) | 2005-11-03 | — | — | WO | disclosed |
| JP-2003146810-A | FLEA CONTROLLING AGENT COMPRISING N-SUBSTITUTED INDOLE DERIVATIVE | NIPPON KAYAKU CO LTD | 2003-05-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135491-A1 | Flea control agent containing n-substitute indole derivative | IDO1, INMT, IDO2 | MAPT 4381/4885ALDH1A1 1403/4885NPSR1 788/4885 |
| US-20090270459-A1 | Flea control agent containing N-Substituted indole derivative | IDO1, IDO2, DDT | MAPT 4341/4885ALDH1A1 1348/4885NPSR1 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.