SCHEMBL4297199

SCHEMBL4297199

CC(C)(C)OC(=O)N1CC(O[Si](C)(C)C(C)(C)C)C[C@@H]1CCNC(=O)CCl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.36
NR1H2 P55055 1/20 0.30
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9142734 0.89 ABCB1 (0.40) ABCB1NR1H2
SCHEMBL8429906 0.87 NR1H2 (0.34) ABCB1NR1H2
SCHEMBL9567173 0.83 NR1H2 (0.37) ABCB1NR1H2
SCHEMBL9140070 0.83 ABCB1 (0.43) ABCB1
SCHEMBL9137756 0.83 ABCB1 (0.40) ABCB1TGM2
SCHEMBL4300309 0.82 ABCB1 (0.34) ABCB1NR1H2
SCHEMBL17152840 0.82 NR1H2 (0.34) ABCB1NR1H2
SCHEMBL8430093 0.82 NR1H2 (0.34) ABCB1NR1H2
SCHEMBL12431668 0.81 NR1H2 (0.37) ABCB1NR1H2
SCHEMBL17152942 0.81 ABCB1 (0.42) ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014021441-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-06 WO disclosed
WO-2009139358-A1 TRIARYLAMINE DERIVATIVE, LIGHT-EMITTING SUBSTANCE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-11-19 WO disclosed
WO-2009131973-A1 QUINOLONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS JANSSEN PHARMACEUTICA NV (BE) 2009-10-29 WO disclosed