Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 4/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567173 | 0.89 | NR1H2 (0.37) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL17152840 | 0.88 | NR1H2 (0.34) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL8430093 | 0.88 | NR1H2 (0.34) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL12431668 | 0.87 | NR1H2 (0.37) | NR1H2ABCB1PIK3CDALDH1A1CHRM2 | |
| SCHEMBL4420095 | 0.87 | ABCB1 (0.35) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL8107559 | 0.87 | NR1H2 (0.36) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4421658 | 0.87 | ABCB1 (0.35) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL9596446 | 0.87 | ABCB1 (0.35) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4297199 | 0.87 | ABCB1 (0.36) | NR1H2ABCB1 | |
| SCHEMBL8113817 | 0.86 | NR1H2 (0.36) | NR1H2ABCB1ALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958817-A1 | COMPOSITION CONTAINING DIARYLALKANE DERIVATIVE AS THE ACTIVE INGREDIENT FOR TREATING OR PREVENTING PANCREATITIS | SANKYO COMPANY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |