⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556851 | 0.80 | — | — | |
| SCHEMBL9193558 | 0.80 | TSHR (0.41) | — | |
| SCHEMBL892657 | 0.79 | — | — | |
| SCHEMBL22729367 | 0.78 | TP53 (0.30) | — | |
| SCHEMBL17169905 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL1951992 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL9314301 | 0.76 | — | — | |
| SCHEMBL22729368 | 0.76 | — | — | |
| SCHEMBL203645 | 0.76 | — | — | |
| SCHEMBL5178393 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466176-B | Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase | 江西帝劢药业有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-115466176-A | Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase | 江西帝劢药业有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-112047818-A | Green method for preparing chloroacetaldehyde dialkyl acetal from vinyl acetate | 石家庄欧特佳化工有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-111246917-A | Pharmaceutical composition comprising remogliflozin and an antidiabetic drug | 格兰马克药品有限公司 | 2020-06-05 | — | — | CN | claimed |
| EP-2914687-A2 | SOLUBLE POLYMERS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-09-09 | — | — | EP | claimed |
| CN-104592249-A | Low-cost simple method for preparing clopidogrel free alkali | XINFA PHARMACEUTICAL CO LTD | 2015-05-06 | — | — | CN | claimed |
| WO-2014068337-A2 | SOLUBLE POLYMERS | THE UNIVERSITY OF LIVERPOOL (GB) | 2014-05-08 | — | — | WO | claimed |
| CN-101695510-A | Method for extracting poplar bark lipoid | JING WANG | 2010-04-21 | — | — | CN | claimed |
| EP-0202157-B1 | N-SUBSTITUTED 2-AMINO-THIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | LABORATOIRES CHAUVIN S.A. (FR) | 1989-08-23 | — | — | EP | claimed |
| US-4532338-A | Halogenating vinyl acetate, reacting product with diol, contacting with aqueous alkaline reagent to hydrolyze by-products, separating phases, heating organic phase to remove volatiles | PPG INDUSTRIES, INC. (US) | 1985-07-30 | — | — | US | claimed |
| JP-59204178-A | — | — | None | — | — | JP | disclosed |
| EP-4632110-A1 | PROCESS FOR THE HALOGENATION OF ORGANIC COMPOUNDS | ESy-Labs-GmbH (DE) | 2025-10-15 | — | — | EP | disclosed |
| CN-119841805-A | Method for continuously producing 2, 5-dihydroxyl-1, 4-dithiane | 上海创诺医药集团有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119306578-A | Method for efficiently preparing chloroacetaldehyde dialkyl acetal through continuous flow | 江西帝劢药业有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115466176-B | Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase | 江西帝劢药业有限公司 | 2024-08-23 | — | — | CN | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4156787-A | HYDROGENATION CATALYST | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001909-A1 | Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4080466-A | LIVER DISORDERS | NIHON NOHYAKU CO., LTD. (JA) | 1978-03-21 | — | — | US | disclosed |