SCHEMBL4297352

SCHEMBL4297352

CC(=O)OC(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7556851 0.80
SCHEMBL9193558 0.80 TSHR (0.41)
SCHEMBL892657 0.79
SCHEMBL22729367 0.78 TP53 (0.30)
SCHEMBL17169905 0.77 TSHR (0.37)
SCHEMBL1951992 0.77 TSHR (0.42)
SCHEMBL203645 0.76
SCHEMBL22729368 0.76
SCHEMBL9314301 0.76
SCHEMBL202087 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115466176-B Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase 江西帝劢药业有限公司 2024-08-23 CN claimed
CN-115466176-A Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase 江西帝劢药业有限公司 2022-12-13 CN claimed
CN-112047818-A Green method for preparing chloroacetaldehyde dialkyl acetal from vinyl acetate 石家庄欧特佳化工有限公司 2020-12-08 CN claimed
CN-111246917-A Pharmaceutical composition comprising remogliflozin and an antidiabetic drug 格兰马克药品有限公司 2020-06-05 CN claimed
EP-2914687-A2 SOLUBLE POLYMERS THE UNIVERSITY OF LIVERPOOL (GB) 2015-09-09 EP claimed
CN-104592249-A Low-cost simple method for preparing clopidogrel free alkali XINFA PHARMACEUTICAL CO LTD 2015-05-06 CN claimed
WO-2014068337-A2 SOLUBLE POLYMERS THE UNIVERSITY OF LIVERPOOL (GB) 2014-05-08 WO claimed
CN-101695510-A Method for extracting poplar bark lipoid JING WANG 2010-04-21 CN claimed
EP-0202157-B1 N-SUBSTITUTED 2-AMINO-THIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE LABORATOIRES CHAUVIN S.A. (FR) 1989-08-23 EP claimed
US-4532338-A Halogenating vinyl acetate, reacting product with diol, contacting with aqueous alkaline reagent to hydrolyze by-products, separating phases, heating organic phase to remove volatiles PPG INDUSTRIES, INC. (US) 1985-07-30 US claimed
JP-59204178-A None JP disclosed
EP-4632110-A1 PROCESS FOR THE HALOGENATION OF ORGANIC COMPOUNDS ESy-Labs-GmbH (DE) 2025-10-15 EP disclosed
CN-119841805-A Method for continuously producing 2, 5-dihydroxyl-1, 4-dithiane 上海创诺医药集团有限公司 2025-04-18 CN disclosed
CN-119306578-A Method for efficiently preparing chloroacetaldehyde dialkyl acetal through continuous flow 江西帝劢药业有限公司 2025-01-14 CN disclosed
CN-115466176-B Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase 江西帝劢药业有限公司 2024-08-23 CN disclosed
US-4189610-A Preparation of 4,4-dioxy-substituted stilbenes MONSANTO COMPANY (US) 1980-02-19 US disclosed
US-4156787-A HYDROGENATION CATALYST MONSANTO COMPANY (US) 1979-05-29 US disclosed
EP-0001910-A1 Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof MONSANTO COMPANY (US) 1979-05-16 EP disclosed
EP-0001909-A1 Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation MONSANTO COMPANY (US) 1979-05-16 EP disclosed
US-4080466-A LIVER DISORDERS NIHON NOHYAKU CO., LTD. (JA) 1978-03-21 US disclosed