SCHEMBL22729367

SCHEMBL22729367

O=C(OC(Cl)CCl)OC(Cl)CCl

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314301 0.80
SCHEMBL22729368 0.80
SCHEMBL608727 0.78
SCHEMBL1041196 0.78
SCHEMBL5327693 0.78 TP53 (0.33) TP53TSHRTDP1
SCHEMBL4297352 0.78
SCHEMBL610657 0.74
SCHEMBL609000 0.74 ALDH1A1 (0.35)
SCHEMBL5178393 0.74
SCHEMBL14990888 0.73 ALDH1A1 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1055771-C Organic photoconductive drum for laser printer and method for manufacturing the same CHINESE ACAD INST CHEMISTRY (CN) 2000-08-23 CN claimed
CN-1144343-A Organic photoconductive drum for laser printer and method for manufacturing the same CHINESE ACAD INST CHEMISTRY (CN) 1997-03-05 CN claimed
CN-111511737-B Monocyclic beta-lactam compounds for the treatment of bacterial infections 南京明德新药研发有限公司 2022-10-18 CN disclosed
US-11459323-B2 Monocyclic β-lactam compound for treating bacterial infection MEDSHINE DISCOVERY INC. (CN) 2022-10-04 US disclosed
CN-113388266-B Pearlescent pigment dispersion coating method and pearlescent effect polycarbonate plate 北京航天凯恩化工科技有限公司 2022-04-01 CN disclosed
CN-113388266-A Pearlescent pigment dispersion coating method and pearlescent effect polycarbonate plate 北京航天凯恩化工科技有限公司 2021-09-14 CN disclosed
US-20210115035-A1 MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION Shenzhen Optimum Biological Technology Co., Ltd (CN) 2021-04-22 US disclosed
EP-3747883-A1 MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION Medshine Discovery Inc. (CN) 2020-12-09 EP disclosed
CN-111511737-A Monocyclic β -lactam compounds for the treatment of bacterial infections 南京明德新药研发有限公司 2020-08-07 CN disclosed
CN-105355700-B A kind of photodetector 北京大学 2018-06-12 CN disclosed
CN-107615555-A Non-aqueous electrolyte for secondary battery and the secondary cell for possessing it 斯泰拉化工公司 2018-01-19 CN disclosed
CN-107431245-A Non-aqueous electrolyte for secondary battery and the secondary cell for possessing it 斯泰拉化工公司 2017-12-01 CN disclosed
CN-107408732-A Non-aqueous electrolyte for secondary battery and the secondary cell for possessing it 斯泰拉化工公司 2017-11-28 CN disclosed
CN-107210487-A Non-aqueous electrolyte for secondary battery and the secondary cell for possessing it 斯泰拉化工公司 2017-09-26 CN disclosed
CN-101503520-B Method for removing solvent by polycarbonate solution aqueous phase precipitation CHINA NAT BLUESTAR GROUP CO 2011-08-31 CN disclosed
CN-101503520-A Method for removing solvent by polycarbonate solution aqueous phase precipitation CHINA NAT BLUESTAR GROUP CO LT (CN) 2009-08-12 CN disclosed
CN-100351309-C Underlayer coating forming composition for lithography containing compound having protected carboxyl group NISSAN CHEMICAL IND LTD (JP) 2007-11-28 CN disclosed
CN-1830202-A Composition for forming lower layer film for lithography comprising compound having protected carboxyl group NISSAN CHEMICAL IND LTD (JP) 2006-09-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459323-B2 Monocyclic β-lactam compound for treating bacterial infection PEPD, COASY, MRPL21 TP53 4483/4885TSHR 4619/4885TDP1 4856/4885
US-20210115035-A1 MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION COASY, BCAT2, PEPD TP53 4500/4885TSHR 4571/4885TDP1 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.